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Assessment of Resistance to Tyrosine Kinase Inhibitors by an Interrogation of Signal Transduction Pathways by Antibody Arrays
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Assessment of Resistance to Tyrosine Kinase Inhibitors by an Interrogation of Signal Transduction Pathways by Antibody Arrays

Published on: September 19, 2018

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Quantifying the strength of heterointeractions among receptor tyrosine kinases from different subfamilies:

Michael D Paul1,2, Hana N Grubb1, Kalina Hristova3,2,4

  • 1Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, Maryland, USA.

The Journal of Biological Chemistry
|May 30, 2020
PubMed

Keywords:
EPH receptor A2 (EPHA2)cell signalingepidermal growth factor receptor (EGFR)fibroblast growth factor receptor (FGFR)fluorescence resonance energy transfer (FRET)membrane proteinprotein-protein interactionreceptor tyrosine kinasereceptor tyrosine kinase (RTK)thermodynamicsvascular endothelial growth factor receptor 2 (VEGFR2)

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