Delayed presentation of acute ischemic strokes during the COVID-19 crisis

Clemens M Schirmer1,2,3, Andrew J Ringer4, Adam S Arthur5,6

  • 1Department of Neurosurgery and Neuroscience Institute, Geisinger Health System, Wilkes-Barre, PA, United States cmschirmer@gmail.com.

Insights

The COVID-19 pandemic caused delays in emergency care, with acute ischemic stroke patients presenting later to stroke centers. This study found a significant increase in the time from last-known-well to presentation during the pandemic.

Area of Science:

  • Neurology
  • Public Health
  • Epidemiology

Background:

  • The COVID-19 pandemic significantly altered global healthcare access and patient behavior.
  • Public awareness and restrictions impacted the perceived urgency for seeking care for acute conditions.

Purpose of the Study:

  • To investigate delays in presentation for acute ischemic stroke patients during the initial phase of the COVID-19 pandemic in the US.
  • To compare presentation times and stroke severity before and during the pandemic.

Main Methods:

  • Retrospective analysis of 710 acute ischemic stroke patients across 12 US stroke centers.
  • Comparison of presentation intervals (last-known-well to presentation) between a baseline period (Feb-Mar 2019) and the early pandemic period (Feb-Mar 2020).

Main Results:

  • A decrease in patient volume was observed during the early pandemic months (227 in Feb 2020, 163 in Mar 2020) compared to the baseline (320 total).
  • No significant differences in stroke severity or patient age were found between the periods.
  • The mean interval from last-known-well to presentation was significantly longer during the COVID-19 period (603 min) versus the baseline (442 min).

Conclusions:

  • Findings suggest a link between public awareness of the pandemic, imposed limitations, and delayed presentation of acute ischemic stroke patients.
  • The study highlights a critical need to address public perception and access to emergency care during public health crises.
Abstract

Related Concept Videos

Acute Coronary Syndrome IV: Interprofessional Care01:28

Acute Coronary Syndrome IV: Interprofessional Care

IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
159
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
287
Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
560
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
142
Acute Coronary Syndrome V: Nursing Management01:26

Acute Coronary Syndrome V: Nursing Management

Nursing Assessment:Nursing management of acute coronary syndrome (ACS) involves taking the patient's history, focusing on primary complaints such as chest pain, dyspnea, and excessive sweating (diaphoresis), as well as other symptoms like back or jaw pain, nausea, vomiting, palpitations, dizziness, and fatigue. The nurse also reviews the patient's history of cardiac events, risk factors such as hypertension, diabetes, smoking, family history, and current medications.In the objective assessment,...
195
Ischemic Heart Disease: Overview01:17

Ischemic Heart Disease: Overview

Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
2.6K