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The Tumor Microenvironment

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...

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Related Experiment Video

Updated: Dec 20, 2025

Enrichment and Characterization of the Tumor Immune and Non-immune Microenvironments in Established Subcutaneous Murine Tumors

Enrichment and Characterization of the Tumor Immune and Non-immune Microenvironments in Established Subcutaneous Murine Tumors

Published on: June 7, 2018

Probing the tumor micro(b)environment

Chloe E Atreya¹, Peter J Turnbaugh^2,3

¹Department of Medicine, Division of Hematology and Oncology, and Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, USA.

Science (New York, N.Y.)

|May 30, 2020

Summary

No abstract available in PubMed .

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Last Updated: Dec 20, 2025

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