Fungal Infection: A Rare Cause Of Gastric Perforation

Rohan Habib1, Muhammad Waqas Afzal1, Fahad Ahmed2

  • 1Department of Surgery, Ayub Teaching Hospital, Abbottabad, Pakistan.

Insights

Invasive fungal infection caused gastric perforation in a 70-year-old man, a rare but critical diagnosis for upper gastrointestinal perforations in elderly patients. This case highlights the need to consider fungal causes in differential diagnoses.

Area of Science:

  • Gastroenterology
  • Infectious Diseases
  • Pathology

Background:

  • Gastric perforation is a frequent surgical emergency often linked to peptic ulcers, NSAID use, or malignancy.
  • Laparotomy is a common surgical procedure for managing gastric perforations.
  • Identifying the underlying cause is crucial for effective treatment and patient outcomes.

Observation:

  • A 70-year-old male presented with gastric perforation.
  • Histopathological examination revealed invasive fungal infection as the cause.
  • This etiology is uncommon compared to typical causes like ulcers or NSAIDs.

Findings:

  • The study documents a rare case of gastric perforation attributed to invasive fungal infection.
  • Histopathological evidence confirmed the fungal etiology.
  • This represents a novel finding in the country, with no prior reported cases.

Implications:

  • Invasive fungal infection should be considered in the differential diagnosis of upper gastrointestinal perforation, particularly in elderly patients.
  • Awareness of this rare cause can improve diagnostic accuracy and patient management.
  • Further research may be warranted to understand the prevalence and risk factors for fungal-induced gastric perforations.

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