Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Higher Mental Functions of the Brain: Language01:10

Higher Mental Functions of the Brain: Language

3.1K
Language is a system of communication that allows the expression of thoughts, ideas, and feelings. The brain processes language in both hemispheres.
Language formation and comprehension take place in the dominant hemisphere. The dominant hemisphere is responsible for understanding the meaning of spoken, written, or sign language, as well as the ability to communicate. For most people, the left hemisphere is the dominant one. The right hemisphere, then, gives tone and emotional context to the...
3.1K
Visual Agnosia01:12

Visual Agnosia

747
Visual agnosia is a condition characterized by the inability to recognize visually presented objects despite having normal vision. For instance, a person with visual agnosia can describe the shape and color of an object but cannot identify or name it. This impairment does not affect their visual field, acuity, color vision, brightness discrimination, language, or memory. An example of this condition in a social setting is someone at a dinner party asking for "that silver thing with a round...
747
Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

1.5K
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
1.5K
Interference and Decay01:16

Interference and Decay

359
Forgetting is a complex cognitive phenomenon influenced by several factors, among which interference and decay are particularly prominent. These processes explain why individuals often struggle to retrieve specific information from memory, leading to lapses in recall that can be observed in everyday situations.
Interference occurs when competing memories hinder the retrieval of particular information. It can be classified into two types: proactive and retroactive interference. Proactive...
359
Amyloid Fibrils03:03

Amyloid Fibrils

6.2K
6.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Neuroinflammation and drug-resistant epilepsy: interleukin 6 as a possible marker].

Medicina·2026
Same author

Affordances and constraints of assistive technology for students with visual impairment at a public university in the United Arab Emirates: a phenomenological study.

Disability and rehabilitation. Assistive technology·2026
Same author

Artificial inoculation of native endophytic fungi and Epichloë in Bromus valdivianus Phil.: successful establishment and growth promotion.

Fungal biology·2026
Same author

Resilience as a Mediator Between Burnout and Health Among Nurses During the COVID-19 Pandemic: A Cross-Sectional Survey in Late 2021.

Nursing open·2026
Same author

Genomic analysis of the inbreeding load for body weight, carcass and reproductive traits in the Rubia Gallega beef cattle population.

Genetics, selection, evolution : GSE·2026
Same author

Symbiosis Between <i>Epichloë</i> Fungi and <i>Bromus</i> Grasses: A Review of Current Knowledge and Future Directions.

Journal of fungi (Basel, Switzerland)·2025

Related Experiment Video

Updated: Dec 20, 2025

A Protocol for Comprehensive Assessment of Bulbar Dysfunction in Amyotrophic Lateral Sclerosis ALS
12:43

A Protocol for Comprehensive Assessment of Bulbar Dysfunction in Amyotrophic Lateral Sclerosis ALS

Published on: February 21, 2011

35.7K

Intrusion errors during verbal fluency task in amyotrophic lateral sclerosis.

Manuel Perez1, Imanol Amayra1, Esther Lazaro1

  • 1University of Deusto, Vizcaya, Spain.

Plos One
|May 30, 2020
PubMed
Summary
This summary is machine-generated.

Amyotrophic lateral sclerosis (ALS) patients show cognitive decline, particularly in verbal fluency tasks. Increased intrusions during these tasks indicate cognitive deterioration, independent of motor impairment.

More Related Videos

Eye-Tracking Control to Assess Cognitive Functions in Patients with Amyotrophic Lateral Sclerosis
07:00

Eye-Tracking Control to Assess Cognitive Functions in Patients with Amyotrophic Lateral Sclerosis

Published on: October 13, 2016

8.6K
Study Design for Navigated Repetitive Transcranial Magnetic Stimulation for Speech Cortical Mapping
09:16

Study Design for Navigated Repetitive Transcranial Magnetic Stimulation for Speech Cortical Mapping

Published on: March 24, 2023

1.8K

Related Experiment Videos

Last Updated: Dec 20, 2025

A Protocol for Comprehensive Assessment of Bulbar Dysfunction in Amyotrophic Lateral Sclerosis ALS
12:43

A Protocol for Comprehensive Assessment of Bulbar Dysfunction in Amyotrophic Lateral Sclerosis ALS

Published on: February 21, 2011

35.7K
Eye-Tracking Control to Assess Cognitive Functions in Patients with Amyotrophic Lateral Sclerosis
07:00

Eye-Tracking Control to Assess Cognitive Functions in Patients with Amyotrophic Lateral Sclerosis

Published on: October 13, 2016

8.6K
Study Design for Navigated Repetitive Transcranial Magnetic Stimulation for Speech Cortical Mapping
09:16

Study Design for Navigated Repetitive Transcranial Magnetic Stimulation for Speech Cortical Mapping

Published on: March 24, 2023

1.8K

Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Neurology

Background:

  • Amyotrophic lateral sclerosis with frontotemporal dementia (ALS-FTD) often presents with dysexecutive syndrome.
  • Reduced verbal fluency is a common finding in ALS patients compared to healthy individuals.
  • Qualitative assessments of verbal fluency are valuable for understanding cognitive function, especially when motor impairments are present.

Purpose of the Study:

  • To investigate cognitive differences in verbal fluency between ALS patients and healthy controls.
  • To examine the impact of varying dementia and motor impairment levels in ALS patients on verbal fluency.
  • To identify qualitative indicators of cognitive alteration in ALS patients.

Main Methods:

  • A comparative study involving 42 ALS patients and 42 healthy controls.
  • Extended administration time (2 minutes) for phonemic verbal fluency (PVF) and semantic verbal fluency (SVF) tasks.
  • Analysis focused on qualitative aspects, including perseverations and intrusions, and their clinical correlates.

Main Results:

  • ALS patients produced significantly fewer responses in both PVF and SVF tasks.
  • A notably higher number of intrusions was observed in the ALS group during the PVF task.
  • No significant difference in perseverations was found between ALS patients and controls.

Conclusions:

  • Intrusions during verbal fluency tasks are a valuable indicator of cognitive deterioration in ALS patients.
  • This cognitive decline appears to be independent of motor impairment and behavioral changes.
  • Verbal fluency tasks, particularly the analysis of intrusions, can serve as an easily evaluated marker for cognitive changes in ALS, even retrospectively.