Related Experiment Video
Updated: Dec 20, 2025

A Novel Digital Platform for a Monitored Home-based Cardiac Rehabilitation Program
Published on: April 19, 2019
Effect of cardiac rehabilitation on cognitive function in elderly patients with cardiovascular diseases
Kazuhiro Fujiyoshi1, Yoshiyasu Minami1, Minako Yamaoka-Tojo2
1Department of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
Insights
Regular cardiac rehabilitation (CR) significantly improves cognitive function in elderly patients with cardiovascular diseases. This indicates CR is effective for secondary prevention, enhancing memory and attention.
Area of Science:
- Cardiology
- Geriatrics
- Neuroscience
Background:
- Cognitive function is crucial for secondary prevention in elderly cardiovascular disease patients.
- Cardiac rehabilitation (CR) is a key intervention for cardiovascular disease management.
Purpose of the Study:
- To evaluate the impact of monthly cardiac rehabilitation on cognitive function in elderly patients with cardiovascular diseases.
- To determine if CR improves cognitive performance as part of secondary prevention.
Main Methods:
- Prospective study of 66 elderly patients (≥70 years) with cardiovascular diseases.
- Comparison of cognitive function changes over 6 months between a monthly CR group (n=27) and a non-monthly CR group (n=39).
- Cognitive function assessed using Mini-mental State Examination (MMSE) and Frontal Assessment Battery (FAB).
Main Results:
- Monthly CR group showed a significantly greater improvement in MMSE scores compared to the non-monthly CR group (2.3 vs. -0.1 points, p <0.001).
- Specific MMSE domains, including temporal orientation and attention/calculation, improved significantly more in the monthly CR group.
- Monthly CR was independently associated with improved MMSE scores (effect estimate 1.455, p <0.001).
Conclusions:
- Regular cardiac rehabilitation may enhance cognitive function in elderly patients with cardiovascular diseases.
- These findings support the role of CR in improving cognitive health for secondary cardiovascular prevention.
Background:
Cognitive function is an important factor for secondary prevention in elderly patients with cardiovascular diseases. The objective of this study was to evaluate the impact of cardiac rehabilitation (CR) on the improvement of cognitive function.
Methods:
A total of 66 consecutive elderly patients (≥70 years old) with cardiovascular diseases were prospectively enrolled. The change in cognitive function during 6 months was compared between the patients with monthly CR (at least once per month; n = 27) and those without monthly CR (n = 39). Cognitive function was evaluated using the Mini-mental State Examination (MMSE) and Frontal Assessment Battery (FAB).
Results:
There was no significant difference in baseline characteristics between the 2 groups. The change in the MMSE score was significantly greater in patients with monthly CR than in those without monthly CR (2.3 ± 0.4 vs. -0.1 ± 0.3 points; p <0.001). Among the MMSE items, the change in temporal orientation and attention and calculation was significantly greater in the monthly CR group than in the non-monthly CR group (0.8 ± 0.7 vs. -0.1 ± 0.8 points [p <0.001] and 1.0 ± 1.5 vs. -0.1 ± 0.1 points [p <0.001], respectively). The general linear model revealed that monthly CR (effect estimate, 1.455; 95% confidence interval, 0.747-2.163; p <0.001) was independently associated with the change in the MMSE score.
Conclusions:
Cognitive function may improve with regular CR. These results might partly explain the efficacy of CR for secondary prevention.
More Related Videos
07:01Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment
Published on: September 20, 2020
07:35Author Spotlight: Rehabilitation of Stroke Patients With a Digital Occupational Training System
Published on: December 29, 2023
Related Concept Videos
Cognitive Development During Adulthood
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System
Exercise and Cardiovascular Response
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Pharmacodynamics in Geriatric Patients: Effects of Age
Exercise and Cardiac Output
Sustained exercise increases the muscles' oxygen demand, which can be...
Cardiomyopathy V: Interprofessional Care