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The human cingulum: From the limbic tract to the connectionist paradigm
Igor Lima Maldonado1, Vitor Parente de Matos2, Taryn Ariadna Castro Cuesta3
1UMR Inserm U1253, IBrain, Université de Tours, Tours, France; Le Studium Loire Valley Institute for Advanced Studies, Orleans, France; CHRU de Tours, Tours, France; Departamento de Biomorfologia - Instituto de Ciências da Saúde, Universidade Federal da Bahia, Salvador, Brazil; Programa de Pós-Graduação Em Medicina e Saúde, Universidade Federal da Bahia, Salvador, Brazil.
The cingulum bundle, a key brain pathway, is now understood to connect all cerebral lobes, not just process emotions. This research highlights its expanded role in higher brain functions beyond the limbic system.
Area of Science:
- Neuroscience
- Neuroanatomy
- Cerebral Connectivity
Background:
- The cingulum bundle is a core component of the limbic lobe and Papez circuit, traditionally linked to emotion processing.
- Recent advancements in cerebral connectivity studies have revealed more about the cingulum's complex morphology and functions.
Purpose of the Study:
- To re-evaluate the role of the cingulum bundle in the human brain.
- To challenge the reductionist view of the cingulum as solely part of the limbic system.
Main Methods:
- Review of recent techniques for studying cerebral connectivity.
- Analysis of the cingulum fasciculus' morphology and terminations.
Main Results:
- The cingulum bundle is a long association fasciculus with connections to all cerebral lobes.
- Its involvement in superior functions extends beyond emotion processing.
Conclusions:
- The cingulum bundle's role necessitates a pivotal rethinking.
- It is now perceived as a primary interconnecting apparatus in the medial cerebral hemisphere.
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