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Biomarkers of Contrast-Induced Nephropathy:: Which Ones are Clinically Important?
Carmen D'Amore1, Silvia Nuzzo2, Carlo Briguori1
1Interventional Cardiology Unit, Mediterranea Cardiocentro, Via Orazio 2, Naples 80121, Italy.
Abstract:
Contrast-induced acute kidney injury (CI-AKI) is a common complication after intravascular injection of iodinated contrast media, and it is associated with a prolonged in-hospital stay and unfavorable outcome. CI-AKI occurs in 5% to 20% among hospitalized patients. Its diagnosis relies on the increase in serum creatinine levels, which is a late biomarker of kidney injury. Novel and early serum and urinary biomarkers have been identified to detect kidney damage before the expected serum creatinine increase.
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