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Immunisation issues in patient with mucopolysaccharidosis: A case report
O M Naur1, A Anggraini2, B W Indraswari2
1Universitas Gadjah Mada/Sardjito General Hospital, Public Health and Nursing, Faculty of Medicine, Department of Child Health, Sekip Yogyakarta Indonesia. oktaviani.mulianiarti@gmail.com.
Insights
Infants with Mucopolysaccharidosis (MPS) face higher infection risks and often miss vaccinations. This report highlights challenges in immunizing these children, stressing the need for careful vaccine management and education.
Area of Science:
- Pediatrics
- Immunology
- Genetics
Background:
- Mucopolysaccharidosis (MPS) is a group of rare genetic disorders.
- Infants with MPS are highly susceptible to respiratory infections.
- Vaccinations are critical for preventing severe infections in vulnerable populations.
Observation:
- This case report focuses on the challenges of administering routine immunizations to infants diagnosed with MPS.
- Factors contributing to missed vaccinations in this population were identified.
- The study highlights the importance of understanding vaccine indications and contraindications for MPS patients.
Findings:
- Routine immunizations present unique challenges in infants with Mucopolysaccharidosis (MPS).
- Careful consideration of vaccine administration protocols is necessary.
- Further research on vaccine safety and immunogenicity in MPS is warranted.
Implications:
- Improved vaccination strategies are crucial for protecting infants with MPS from infections.
- Educational programs for parents and healthcare providers are essential for successful immunization.
- Addressing barriers to vaccination can improve health outcomes for children with rare diseases.
Abstract:
Young patients, especially infants with Mucopolysaccharidosis (MPS) have increased risk of recurrent upper and lower respiratory tract infections. A complete schedule of immunisations is crucial to protect children from life-threatening infections. However, in most cases, they often miss scheduled vaccinations due to many factors. This case report describes issues in administering routine immunisations to infants with MPS. It is vital to recognise the indications and contraindications of vaccinations for patients with MPS although all vaccines need detailed study to investigate their safety and immunogenicity. Furthermore, regular educational programs are essential for both parents and health providers.
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