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Updated: Jun 15, 2026

Analysis of Chromosome Segregation, Histone Acetylation, and Spindle Morphology in Horse Oocytes
Published on: May 11, 2017
Antioxidant response element activator, BTZO-1, improves the developmental competence of bovine oocytes
Mansour Aboelenain1,2, Wael B El Domany1, Haitham Eldoumani3
1Department of Theriogenology, Faculty of Veterinary Medicine, Mansoura University, Mansoura, Egypt.
Abstract:
Increased reactive oxygen species (ROS) generation may disrupt the oocytes function and their competence. In this study, we introduced BTZO-1, a new supplement that can regulate the oxidative stress. Addition of BTZO-1 during IVM of bovine oocytes improved their developmental competence in the term of improvement of blastocyst rates. In addition, the quality of the produced embryos was improved by decreasing the apoptosis level by showing a decreased number of TUNNEL positive cells.
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