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Updated: Dec 20, 2025

Author Spotlight: Isolation and Culture of Primary Synovial Macrophages and Fibroblasts from Murine Arthritis Tissue
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Fatigue in inflammatory arthritis.

Emma Dures1, Fiona Cramp2, Kate Hackett3

  • 1Academic Rheumatology, Bristol Royal Infirmary, Bristol, UK; Department of Nursing and Midwifery, University of the West of England, Bristol, UK.

Best Practice & Research. Clinical Rheumatology
|June 1, 2020
PubMed
Summary

Fatigue is a significant challenge for individuals with inflammatory arthritis. This article explores its impact and non-pharmacological management strategies, offering practical tools for clinical practice.

Keywords:
Experiential natureFatigueMulti-disciplinaryNon-pharmacologicalSelf-management

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Area of Science:

  • Rheumatology
  • Psychology
  • Rehabilitation Medicine

Background:

  • Fatigue is a prevalent and debilitating symptom in inflammatory arthritis.
  • Patients describe fatigue as overwhelming and difficult to manage, impacting daily life.
  • A multi-disciplinary approach is needed to understand and manage inflammatory arthritis fatigue.

Purpose of the Study:

  • To explore the experience, impact, and non-pharmacological management of fatigue in inflammatory arthritis.
  • To present qualitative evidence on the physical, cognitive, and emotional aspects of fatigue.
  • To review evidence for non-pharmacological interventions and their clinical implementation.

Main Methods:

  • Qualitative evidence from individuals living with fatigue.
  • Discussion of conceptual models for fatigue mechanisms.
  • Review of research evidence for non-pharmacological interventions.
  • Exploration of fatigue measurement and assessment.

Main Results:

  • Fatigue in inflammatory arthritis is multi-faceted, affecting physical, cognitive, and emotional well-being.
  • Various non-pharmacological interventions show promise in reducing fatigue severity and impact.
  • Understanding mechanisms and accurate assessment are crucial for effective management.

Conclusions:

  • Non-pharmacological strategies are vital for managing inflammatory arthritis fatigue.
  • Evidence-based interventions can be implemented in clinical practice.
  • A multi-disciplinary perspective enhances the understanding and management of fatigue.