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COVID-19-Related Aortic Thrombosis: A Report of Four Cases

Diego Gomez-Arbelaez1, Gabriela Ibarra-Sanchez1, Ania Garcia-Gutierrez1

  • 1Division of Vascular Surgery, Hospital Universitario 12 de Octubre, Madrid, Spain.

Annals of Vascular Surgery
|June 1, 2020
PubMed

Insights

Severe COVID-19 infection increases the risk of blood clots. This study highlights a limited but serious risk of aortic thrombosis and related ischemic events in patients with critical SARS-CoV-2 illness.

Area of Science:

  • Cardiovascular Medicine
  • Infectious Diseases
  • Vascular Surgery

Background:

  • COVID-19 is associated with an elevated risk of thrombotic events.
  • While venous thromboembolism is frequently reported, arterial thrombosis in COVID-19 patients remains less understood.
  • Understanding the spectrum of thrombotic complications is crucial for patient management.

Observation:

  • This report details four cases of aortic thrombosis.
  • These cases occurred in patients with severe SARS-CoV-2 infection.
  • Associated ischemic complications were also observed.

Findings:

  • Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) infection can lead to aortic thrombosis.
  • Aortic thrombosis in COVID-19 patients can result in significant ischemic complications.
  • The pathophysiological mechanisms linking SARS-CoV-2 to arterial thrombosis require further investigation.

Implications:

  • Clinicians should consider the possibility of aortic thrombosis in severe COVID-19 patients presenting with ischemic symptoms.
  • Early recognition and management of arterial thrombosis are essential in this patient population.
  • Further research is needed to elucidate the specific mechanisms and guide preventative strategies.

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