Related Experiment Video
Updated: Dec 20, 2025
10:32
Optimized Protocols for Mycobacterium leprae Strain Management: Frozen Stock Preservation and Maintenance in Athymic Nude Mice
Published on: March 23, 2014
15.5K
Long-term ulcerations caused by Mycobacterium lepromatosis
Ilaria Trave1, Gianfranco Barabino2, Alberto Cavalchini2
1Dermatology Unit, Department of Health Sciences (DISSAL), University of Genoa, San Martino Policlinic Hospital, IRCCS, Genoa, Italy.
International Journal of Mycobacteriology
|June 1, 2020
Summary
Lucio
Area of Science:
- Dermatology
- Infectious Diseases
- Pathology
Background:
- Leprosy, a chronic infectious disease, can manifest with rare ulcerated lesions during reactional states.
- Lucio's phenomenon (LP) is an uncommon complication of multibacillary leprosy.
Observation:
- This case highlights ulcerated lesions as a potential sign of Lucio's phenomenon (LP) in leprosy patients.
- LP involves massive bacilli invasion of endothelial cells, leading to a thrombotic syndrome.
- Lesions progress from purpuric macules to infiltrated papules and nodules, some ulcerating, with associated sensory loss.
Findings:
- Early recognition of leprosy-associated ulcers is crucial for timely diagnosis and treatment.
- Mycobacterium lepromatosis infection is linked to LP and should be investigated in endemic areas.
Implications:
- Identifying these specific cutaneous manifestations can prevent disease progression and long-term disabilities.
- Increased awareness of LP in endemic regions can improve patient outcomes and reduce the burden of leprosy.
Related Concept Videos
01:28Pulmonary Tuberculosis II
1.2K
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
1.2K
01:31Pulmonary Tuberculosis III
795
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
795
01:28Pulmonary Tuberculosis V
465
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
465
01:29Pulmonary Tuberculosis I
741
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
741
01:26Pulmonary Tuberculosis IV
423
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
423
01:31Defense Against Bacterial Pathogens
2.5K
The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
2.5K