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Published on: December 20, 2011
A de Winter electrocardiographic pattern caused by left main coronary artery occlusion: A case report
Zhong-Qun Zhan1, Yang Li1, Li-Hao Wu1
1Department of Cardiology, Shenzhen Hospital-University of Chinese Academy of Sciences, Shenzhen, P.R. China.
Insights
The de Winter electrocardiogram (ECG) pattern, typically indicating left anterior descending artery occlusion, can also signal acute left main coronary artery (LMCA) occlusion. Early recognition of this ECG finding is crucial for life-saving interventions.
Area of Science:
- Cardiology
- Medical Diagnostics
Background:
- The de Winter electrocardiogram (ECG) pattern is a recognized indicator of proximal left anterior descending coronary artery occlusion.
- This ECG pattern is characterized by specific ST depression and T wave abnormalities in precordial leads, often with ST elevation in lead aVR.
Observation:
- A case study presented a patient with an acute left main coronary artery (LMCA) occlusion exhibiting the de Winter ECG pattern in leads V2-V4.
- The patient's ECG also displayed maximal ST depression in leads V4-V5 and inverted T waves in leads V5-V6, suggesting global subendocardial ischemia.
Findings:
- The observed ECG findings in this patient indicated a pattern suggestive of LMCA or three-vessel coronary artery disease.
- This presentation expands the diagnostic utility of the de Winter ECG pattern beyond proximal LAD occlusion.
Implications:
- Early identification of this specific ECG manifestation in acute LMCA occlusion is critical for timely intervention.
- Prompt coronary intervention in cases of acute LMCA occlusion, as suggested by this ECG pattern, can be life-saving and improve patient prognosis.
Abstract:
A de Winter electrocardiographic (ECG) pattern comprising precordial junctional ST depression followed by tall, positive symmetrical T waves in leads V1/V2 to V4/V6 is often concomitant with ST elevation in lead aVR. This finding strongly suggests proximal left anterior descending coronary artery occlusion. We described a patient who had the de Winter ECG pattern in leads V2 to V4 by acute left main coronary artery (LMCA) occlusion. The ECG also showed maximal ST depression in leads V4 to V5 and inverted T waves in leads V5 to V6. This finding indicated a global subendocardial ischemia ECG pattern, which suggested LMCA or three-vessel disease. Early recognition of this ECG manifestation is important for averting a disastrous prognosis in acute LMCA occlusion because emergent coronary intervention may be life-saving.
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