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Metastatic pulmonary calcification in sarcoidosis
1Pulmonary Section, Veterans Administration Medical Center, Washington, DC.
Respiration; International Review of Thoracic Diseases
|January 1, 1988
Summary
A patient with sarcoidosis developed metastatic pulmonary calcification due to elevated vitamin D levels and hypercalcemia. This condition, marked by calcium deposits in the lungs, was confirmed via radioisotope scanning and biopsy.
Area of Science:
- Nephrology
- Pulmonology
- Endocrinology
Background:
- Sarcoidosis is an inflammatory disease that can affect multiple organs.
- Hypercalcemia and elevated 1,25-dihydroxy vitamin D levels are known complications of sarcoidosis.
Observation:
- A patient with sarcoidosis presented with hypercalcemia, nephrolithiasis, and moderate azotemia.
- The patient also developed metastatic pulmonary calcification.
Findings:
- Metastatic pulmonary calcification was diagnosed using radioisotope scanning and tissue biopsy.
- Elevated 1,25-dihydroxy vitamin D levels contributed to hypercalcemia and subsequent calcification.
Implications:
- This case highlights a severe complication of sarcoidosis-related hypercalcemia.
- Early diagnosis and management of hypercalcemia are crucial in sarcoidosis patients to prevent metastatic calcification.