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SAPHO syndrome: A radiological case report.

Anil Kumar Singh1, Rahul S Ranjan2

  • 1Department of Radiodiagnosis, SGPGIMS, Lucknow, India.

The Indian Journal of Radiology & Imaging
|June 2, 2020
PubMed
Summary

This case report highlights synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) syndrome, a rare inflammatory condition. It was incidentally discovered in a male patient presenting with pulmonary symptoms.

Keywords:
Ankylosisarthropathyhyperostosis, osteitispustulosissynovitis–acne–pustulosis–hyperostosis–osteitis

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Area of Science:

  • Rheumatology
  • Dermatology
  • Osteology

Background:

  • SAPHO syndrome is a rare, chronic inflammatory disorder of unknown origin.
  • It is characterized by a distinct pattern of synovitis, acne, pustulosis, hyperostosis, and osteitis.
  • The condition affects multiple organ systems, often presenting diagnostic challenges.

Observation:

  • A middle-aged male patient presented with pulmonary complaints.
  • During the diagnostic workup for his pulmonary issues, SAPHO syndrome was incidentally detected.
  • This highlights the potential for SAPHO syndrome to be asymptomatic or present with atypical symptoms.

Findings:

  • The case demonstrates the incidental diagnosis of SAPHO syndrome.
  • This underscores the importance of considering SAPHO syndrome in differential diagnoses, even with unrelated primary complaints.
  • Detailed investigation revealed the characteristic features of the syndrome.

Implications:

  • This case broadens the understanding of SAPHO syndrome's clinical presentation.
  • It emphasizes the need for heightened awareness among clinicians for early diagnosis and management.
  • Further research into the etiology and optimal treatment strategies for SAPHO syndrome is warranted.