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Updated: Dec 20, 2025

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Etiology, Pathology, and Classification of Atrial Fibrillation
Srishti Nayak1, Balaji Natarajan2, Ramdas G Pai2
1Loma Linda University School of Medicine, Loma Linda, California.
Abstract:
Atrial fibrillation (AF) is a disorganized tachyarrhythmia with significant public health importance due to high morbidity, mortality, and health-care costs. Incidence rate of AF is on the rise and there are several modifiable and nonmodifiable risk factors that are responsible. Exact mechanisms and pathogenesis of AF are still poorly understood, yet they still have great implications in management. The aim of this article is to summarize the epidemiology, major risk factors, and their role in the pathogenesis of AF. Finally, we have reviewed the classification of AF as per professional society guidelines.
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