[Correlation of functional indices of the left ventricle with structural changes in the myocardium]

11 with dilatative cardiomyopathy, 9 with valvular disease and 3 with ischemic heart disease--a full intracardial examination including right ventricular endomyocardial biopsy was performed. The most severe disorders of the hemodynamic parameters were found in the group of patients with dilatative cardiomyopathy. The pressure in the pulmonary artery was the highest of all groups of patients. The initial meane values of the systolic, diastolic and the average pressure were 5.73, 2.53 and 3.73 kPa and after left ventriculography was performed they were 6.80, 3.60 and 5.07 kPa respectively. The values of the ejection fraction were the lowest of all groups of patients. The left ventricular volume was greatly increased. The average telediastolic volume index was 235 ml/m2 and the average telesystolic volume index was 173 ml/m2. The velocity indices were greatly decreased--the average velocity of the circumferential fibers contraction was 0.45 circ/s and the ratio dp/dt was 1062 mm Hg/s. All patients were with normal coronary arteries. The very poor indices of 4 patients indicates for cardiac transplantation are of special interest. In the patients with valvular disease various degree of lowered hemodynamic parameters were found corresponding to the structural changes of the myocardium. In the third group of 3 patients with ischemic heart disease and severe disorders in the left ventricular function massive fibrous changes in the myocardium were found.