Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Mapping neural representations of fine and gross upper-limb movements across dorsoventral subthalamic nucleus subregions in Parkinson's disease.

Journal of neural engineering·2026

Same author

Theta Oscillations, Oculomotor Processing, and Neural Synchronization: A Review.

Brain sciences·2026

Same author

Responsive stimulation of the thalamus for idiopathic generalized epilepsy: Results of the randomized controlled NAUTILUS trial through 18 months.

Epilepsia·2026

Same author

Recruitment feasibility for deep brain stimulation compared to transcranial magnetic stimulation treatment trials for methamphetamine use disorder.

Addictive behaviors reports·2026

Same author

Beyond the Numbers: Quantitative and qualitative analysis of quality of life after deep brain stimulation for OCD.

PloS one·2026

Same author

Postapproval Study for Brain-Responsive Neurostimulation for Drug-Resistant Focal Epilepsy: Three-Year Efficacy and Interim Safety Results.

Neurology·2026

Same journal

Mind the gender gap: how defining head trauma increases reporting in women aged 30-50.

Frontiers in neurology·2026

Same journal

Traditional Chinese medicine interventions for post-stroke cognitive impairment: an evidence mapping.

Frontiers in neurology·2026

Same journal

Acupuncture is independently associated with improved recovery in Guillain-Barré syndrome: a prospective observational study.

Frontiers in neurology·2026

Same journal

A convergence of global epidemics: diabetes as a modulator of neurodegenerative and neuro-inflammatory disorders.

Frontiers in neurology·2026

Same journal

Lumbar puncture opening pressure, brain network hub integrity, and delirium in herpes simplex virus encephalitis: a prospective cohort study.

Frontiers in neurology·2026

Same journal

Sleep deprivation: a comprehensive review of multisystem impacts, underlying mechanisms, and emerging interventions.

Frontiers in neurology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Dec 20, 2025

Recording Human Electrocorticographic ECoG Signals for Neuroscientific Research and Real-time Functional Cortical Mapping

Recording Human Electrocorticographic ECoG Signals for Neuroscientific Research and Real-time Functional Cortical Mapping

Published on: June 26, 2012

Stimulation Mapping Using Stereoelectroencephalography: Current and Future Directions.

Derek D George¹, Steven G Ojemann², Cornelia Drees³

¹School of Medicine, University of Colorado School of Medicine, Aurora, CO, United States.

Frontiers in Neurology

|June 2, 2020

Summary

This summary is machine-generated.

Stereoelectroencephalography (SEEG) electrical stimulation mapping (ESM) is crucial for epilepsy surgery. It precisely identifies the seizure focus and eloquent brain areas, improving surgical planning and outcomes.

Keywords:

electrical stimulation mapping epilepsy epileptogenic zone functional neurosurgery review stereoelectroencephalography subdural grid

More Related Videos

Neuroimaging-Guided TMS–EEG for Real-Time Cortical Network Mapping

Neuroimaging-Guided TMS–EEG for Real-Time Cortical Network Mapping

Published on: June 13, 2025

Author Spotlight: Stimulation-Based Approach to Improve Cerebral Blood Flow in Alzheimer's Model

Author Spotlight: Stimulation-Based Approach to Improve Cerebral Blood Flow in Alzheimer's Model

Published on: June 2, 2023

Related Experiment Videos

Last Updated: Dec 20, 2025

Recording Human Electrocorticographic ECoG Signals for Neuroscientific Research and Real-time Functional Cortical Mapping

Recording Human Electrocorticographic ECoG Signals for Neuroscientific Research and Real-time Functional Cortical Mapping

Published on: June 26, 2012

Neuroimaging-Guided TMS–EEG for Real-Time Cortical Network Mapping

Neuroimaging-Guided TMS–EEG for Real-Time Cortical Network Mapping

Published on: June 13, 2025

Author Spotlight: Stimulation-Based Approach to Improve Cerebral Blood Flow in Alzheimer's Model

Author Spotlight: Stimulation-Based Approach to Improve Cerebral Blood Flow in Alzheimer's Model

Published on: June 2, 2023

Area of Science:

Neuroscience
Neurosurgery
Epileptology

Background:

Electrical stimulation mapping (ESM) via stereoelectroencephalography (SEEG) has been vital since the 1960s for epilepsy surgery.
It remains the gold standard for delineating critical brain regions and seizure onset zones.

Purpose of the Study:

To review the current techniques of SEEG stimulation for identifying the epileptogenic zone and eloquent cortex.
To summarize clinical data on the effectiveness of SEEG stimulation in surgical outcomes and functional mapping.
To highlight future applications of SEEG ESM in epilepsy management and cognitive neuroscience.

Main Methods:

Review of current SEEG stimulation techniques.
Summary of clinical data on surgical outcomes and functional mapping.
Exploration of emerging applications in neurophysiology and guided interventions.

Main Results:

SEEG ESM is unparalleled in defining eloquent cortex and seizure foci.
Clinical data supports the efficacy of SEEG stimulation in improving surgical outcomes.
Future applications include advanced functional mapping and neurophysiologic investigations.

Conclusions:

SEEG ESM is indispensable for surgical epilepsy workup.
It plays a key role in optimizing surgical planning and patient outcomes.
Ongoing advancements promise expanded utility in epilepsy treatment and cognitive research.