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Updated: Dec 20, 2025

Diagonal Method to Measure Synergy Among Any Number of Drugs
Published on: June 21, 2018
Analysis of Inter-Domain and Cross-Domain Drug Review Polarity Classification
Gabrielle Gurdin1, Jorge A Vargas1, Luke G Maffey1
1Virginia Commonwealth University, Richmond, VA.
Abstract:
Individuals increasingly rely on social media to discuss health-related issues. One way to provide easier access to relevant in- formation is through sentiment analysis - classifying text into polarity classes such as positive and negative. In this paper, we generated freely available datasets of WebMD.com drug reviews and star ratings for Common, Cancer, Depression, Diabetes, and Hypertension drugs. We explored four supervised learning models: Naive Bayes, Random Forests, Support Vector Machines, and Convolutional Neural Networks for the purpose of determining the polarity of drug reviews. We conducted inter-domain and cross-domain evaluations. We found that SVM obtained the highest f-measure on average and that cross-domain training produced similar or higher results to models trained directly on their respective datasets.
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