Related Experiment Video

Updated: Dec 20, 2025

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
12:45

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

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His-bundle Pacing to Left Bundle Branch Pacing: Evolution of His-Purkinje Conduction System Pacing

Pugazhendhi Vijayaraman1

  • 1Geisinger Heart Institute, Geisinger Commonwealth School of Medicine, Wilkes Barre, PA, USA.

The Journal of Innovations in Cardiac Rhythm Management
|June 2, 2020
PubMed

Insights

His-bundle pacing (HBP) is a viable alternative to traditional pacing. This report explores pacing the left bundle branch area when standard HBP is not feasible, offering a new option for cardiac resynchronization therapy.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Medical Devices

Background:

  • His-bundle pacing (HBP) is an advanced technique for cardiac pacing.
  • It is increasingly used for patients needing cardiac resynchronization therapy (CRT), especially those with left bundle branch block (LBBB).
  • Standard HBP may face challenges like high pacing thresholds or His bundle disease.

Observation:

  • The feasibility of pacing the left bundle branch (LBB) area distal to the conduction block is examined.
  • This approach targets specific electrical pathways in the heart's conduction system.

Findings:

  • Pacing in the LBB area distal to block presents a potential solution when conventional HBP is unsuccessful.
  • This strategy may improve CRT outcomes in select patient groups.

Implications:

  • This technique expands the options for His-bundle pacing and CRT.
  • It offers a promising alternative for patients with complex conduction abnormalities.
  • Further research is warranted to establish the long-term efficacy and safety of this pacing strategy.

Keywords:
Biventricular pacingHis-bundle pacingcardiac resynchronization therapyleft bundle branch area pacingleft bundle branch block

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