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Updated: Dec 20, 2025

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
12:45

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

10.8K

Cardiac Resynchronization Therapy in Pediatrics

Allison C Hill1,2, Michael J Silka1,2, Yaniv Bar-Cohen1,2

  • 1Division of Cardiology, Children's Hospital Los Angeles, Los Angeles, CA, USA.

The Journal of Innovations in Cardiac Rhythm Management
|June 2, 2020
PubMed

Insights

Cardiac resynchronization therapy (CRT) offers benefits for adults with heart failure. While pediatric applications are less defined due to heterogeneity, initial results for CRT in children are promising.

Area of Science:

  • Pediatric Cardiology
  • Cardiovascular Medicine
  • Biomedical Engineering

Background:

  • Cardiac resynchronization therapy (CRT) is established for adult heart failure with specific criteria (e.g., LBBB, low ejection fraction).
  • Pediatric heart failure presents diverse etiologies and anatomical variations, often not aligning with adult CRT guidelines.
  • Identifying suitable pediatric candidates for CRT remains challenging due to population heterogeneity.

Purpose of the Study:

  • To review current indications for CRT in pediatric patients.
  • To analyze outcomes of CRT in pediatric populations, including those with congenital heart disease.
  • To explore the potential of CRT in a heterogeneous pediatric group.

Main Methods:

  • Review of existing literature on pediatric CRT.
  • Analysis of case studies and clinical trial data for pediatric heart failure patients.
  • Comparison of adult and pediatric CRT criteria and outcomes.

Main Results:

  • Initial experiences with CRT in pediatric patients have shown encouraging outcomes across various subgroups.
  • CRT may offer benefits beyond typical adult indications in specific pediatric cases.
  • Further research is needed to refine pediatric CRT selection criteria.

Conclusions:

  • CRT is a developing therapeutic option for pediatric heart failure.
  • Tailoring CRT to pediatric-specific conditions is crucial for success.
  • Ongoing studies aim to optimize CRT utilization in children with heart conditions.

Keywords:
Cardiac resynchronization therapyheart failurepediatrics

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