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Modified insertion technique for a sustained-release dexamethasone intravitreal implant (Ozurdex®)
Daniel H Lee1, Clement K Chan2,3
1Department of Internal Medicine, Mayo Clinic, 13400, E. Shea Blvd., Scottsdale, AZ, USA.
This new technique secures the sustained-release dexamethasone implant (Ozurdex®) to the vitreous base, preventing complications like anterior chamber migration and visual disturbances from free-floating implants.
Area of Science:
- Ophthalmology
- Retina Surgery
Background:
- Intravitreal sustained-release dexamethasone implants (Ozurdex®) are used for various retinal conditions.
- Conventional insertion techniques can lead to implant dislocation and associated complications.
Observation:
- A modified intravitreal injection technique was developed, altering needle orientation to adhere the Ozurdex® implant to the vitreous base.
- This technique was successfully applied in two patients: one with a dislocated implant and another experiencing visual disturbance from a free-floating implant.
Findings:
- The modified technique effectively adhered the Ozurdex® implant to the vitreous base in both cases.
- No postoperative complications were observed in either patient following the modified insertion procedure.
Implications:
- This modified Ozurdex® insertion method offers a potential solution to prevent implant-related adverse events.
- It may improve patient outcomes and reduce the need for interventions related to implant dislocation or visual disturbance.
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