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Association between obesity and venous thromboembolism
12 Internal Medicine Department, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Medicine and Pharmacy Reports
|June 2, 2020
Summary
Obesity is an independent risk factor for venous thromboembolism (VTE). The risk of VTE increases with obesity class, age, and other acquired risk factors, highlighting a significant public health concern.
Area of Science:
- Medical Science
- Public Health
- Epidemiology
Background:
- Obesity is linked to various health issues, including venous thromboembolism (VTE).
- Hospitalized patients face a high risk of VTE, a complex condition.
- Understanding obesity's role in VTE is crucial for patient management.
Purpose of the Study:
- To evaluate the association between obesity and VTE risk.
- To analyze how obesity class, age, and gender influence VTE risk.
- To determine the impact of co-existing risk factors on VTE development in obese individuals.
Main Methods:
- A case-control study involving 732 patients.
- Data collected included BMI, age, gender, and acquired VTE risk factors.
- Logistic regression analysis identified independent risk factors for VTE.
Main Results:
- Obesity demonstrated a 6.2-fold increased risk of VTE.
- VTE risk was highest in obese patients over 50 and those with Class II/III obesity.
- Obesity independently predicted VTE risk in both genders, with combined risk factors nearly doubling VTE occurrence.
Conclusions:
- Obesity is confirmed as an independent, moderate risk factor for VTE.
- Increased BMI, advanced age, and additional risk factors amplify VTE risk in obese individuals.
- These findings underscore the importance of weight management in VTE prevention strategies.
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