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Relationship between placental shape, cord insertion, lobes and gestational outcome
M Nordenvall1, B Sandstedt, U Ulmsten
1Department of Obstetrics & Gynaecology, Danderyd Hospital, Sweden.
Acta Obstetricia Et Gynecologica Scandinavica
|January 1, 1988
Summary
Placental abnormalities, including marginal cord insertion and fewer lobes, are linked to adverse pregnancy outcomes like pre-eclampsia and smaller infant size. A low lobe count appears to be a key factor in these abnormal placental configurations and outcomes.
Area of Science:
- Obstetrics and Gynecology
- Perinatal Medicine
- Placental Biology
Background:
- Placental morphology influences pregnancy and perinatal outcomes.
- Understanding variations in placental structure is crucial for risk assessment.
Purpose of the Study:
- To investigate correlations between placental factors (size, shape, cord insertion, vascular pattern, lobes) and pregnancy/perinatal outcomes.
- To identify common denominators for abnormal placental configurations.
Main Methods:
- Examination of 330 singleton placentas.
- Assessment of placental size, shape, cord insertion, allanto-chorial vascular pattern, and lobe count.
- Correlation analysis with pregnancy and perinatal outcomes.
Main Results:
- Marginal cord insertion associated with extrachorial placenta, bilobate placenta, and specific vascular patterns.
- A paucity of lobes (<15) linked to extrachorial placenta, marginal cord insertion, pre-eclampsia, preterm birth (<38 weeks), and small for gestational age infants.
- Paucity of lobes identified as a potential common factor for abnormal placental configuration and marginal cord insertion.
Conclusions:
- Placental lobe count is a significant indicator of placental morphology and potential adverse outcomes.
- Abnormal placental features, particularly a paucity of lobes, are associated with increased risk for pre-eclampsia and fetal growth restriction.