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The status and trends of coronavirus research: A global bibliometric and visualized analysis

Xingjia Mao1, Lu Guo2, Panfeng Fu3

  • 1Orthopedic Department, Second Hospital of Shanxi Medical University, Taiyuan.

Medicine
|June 3, 2020
PubMed

Insights

Global coronavirus research surged with outbreaks like SARS and MERS. Current focus includes spike protein, receptor binding domain, and vaccine development for future epidemic preparedness.

Area of Science:

  • Virology and Epidemiology
  • Infectious Disease Research

Background:

  • The emergence of novel coronaviruses, including SARS-CoV and the virus causing COVID-19, highlights the critical need for robust research.
  • Understanding global research trends is essential for effective epidemic response and prevention.

Purpose of the Study:

  • To investigate the global status and trends in coronavirus research.
  • To identify key research areas, influential institutions, and funding bodies.

Main Methods:

  • Bibliometric analysis of 9,294 publications from 2003 to 2020, sourced from the Web of Science database.
  • Utilized VOSviewer and GraphPadPrism for bibliometric coupling, co-authorship, co-citation, and co-occurrence analyses.
  • Examined publication trends and keyword clusters.

Main Results:

  • Publication output significantly increased following the SARS (2004) and MERS (2012) outbreaks.
  • The USA led in publications and citations; Netherlands had the highest average citations per item.
  • Key research clusters identified: Pathological, Epidemiological, Clinical, and Mechanistic research.

Conclusions:

  • Epidemic outbreaks stimulate coronavirus research, which in turn aids in overcoming them.
  • Emerging research areas include spike protein, receptor binding domain, and vaccine development.
  • Future efforts should prioritize mechanistic and vaccine research for enhanced epidemic preparedness.
Abstract

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