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Efficacy and safety of acupuncture therapy for COVID-19: A protocol for systematic review and meta-analysis
Shaolei Huang1, Suyao Wang2, Mengmeng Wang1
1Shandong University of Traditional Chinese Medicine.
Insights
This systematic review evaluates acupuncture's effectiveness and safety for COVID-19. It synthesizes evidence on outcomes like mortality, cure rates, and symptom resolution, providing crucial insights for this emerging therapy.
Area of Science:
- Integrative Medicine
- Infectious Diseases
- Evidence-Based Practice
Background:
- Coronavirus disease 2019 (COVID-19) presents a significant global health challenge.
- Investigating complementary therapies like acupuncture is crucial for comprehensive patient care.
- Existing research on acupuncture for COVID-19 requires systematic evaluation.
Purpose of the Study:
- To systematically evaluate the efficacy and safety of acupuncture therapy in managing COVID-19.
- To synthesize current evidence regarding acupuncture's impact on key clinical outcomes in COVID-19 patients.
- To provide a comprehensive overview of acupuncture's potential role in COVID-19 treatment.
Main Methods:
- A comprehensive literature search of multiple electronic databases (Medline, PubMed, EMBASE, etc.) was conducted from December 2019 to December 2020.
- Inclusion criteria focused on published randomized controlled trials investigating acupuncture for COVID-19.
- Data extraction, quality assessment, and meta-analysis (where applicable) were performed by two independent researchers using Review Manager (V.5.3.5).
Main Results:
- The synthesis will analyze data on mortality rates, cure rates, and time to negative nucleic acid detection.
- Improvements in chest CT scans, fever, and cough resolution times will be assessed.
- The incidence and nature of any reported side effects associated with acupuncture treatment will be documented.
Conclusions:
- This study aims to determine if acupuncture is a viable and safe therapeutic option for COVID-19.
- The findings will inform clinical practice and future research directions regarding acupuncture for viral respiratory infections.
- Evidence synthesis will clarify acupuncture's role in improving patient outcomes and reducing symptom duration in COVID-19.
Background:
The study aims to evaluate the effectiveness and safety of acupuncture therapy for coronavirus disease 2019.
Methods:
The following electronic databases will be searched from December 2019 to December 2020: Medline, PubMed, EMBASE, Web of Science, China National Knowledge Infrastructure, Wan-fang database, Chinese Scientific Journal Database, Chinese Biomedical Literature Databases, and other databases. All published randomized controlled trials about this topic will be included. Two independent researchers will operate article retrieval, duplication removing, screening, quality evaluation, and data analyses by Review Manager (V.5.3.5). Meta-analyses, subgroup analysis, and/or descriptive analysis will be performed based on the included data conditions.
Results:
High-quality synthesis and/or descriptive analysis of current evidence will be provided from mortality rate, cure rate, the time of negative nucleic acid detection for 2 consecutive times (not on the same day), improvement of chest CT scans, disappearance time of fever and cough, and side effects.
Conclusion:
This study will provide the evidence of whether acupuncture is an effective and safe intervention for coronavirus disease 2019 .PROSPERO registration number: CRD42020179298.
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