Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Synergy of spiritual ambience, sattvic dietary regimen, homely care, and conventional medical therapy in the holistic rehabilitation of a terminally ill patient with post-traumatic complications: A case report.

Explore (New York, N.Y.)·2025
Same author

Prevalence of MRSA in Livestock, Including Cattle, Farm Animals, and Poultry, in Mainland China, Hong Kong Special Administrative Region, Sri Lanka, and Bangladesh: A Systematic Review and Meta-Analysis.

Microorganisms·2025
Same author

Antivirulence Properties of Kuraridin Against Methicillin-Resistant <i>Staphylococcus aureus</i> (MRSA).

Biomedicines·2025
Same author

From Clinical to Benchside: Lacticaseibacillus and Faecalibacterium Are Positively Associated With Muscle Health and Alleviate Age-Related Muscle Disorder.

Aging cell·2025
Same author

Therapeutic Potential of Silver Nanoparticles (AgNPs) as an Antimycobacterial Agent: A Comprehensive Review.

Antibiotics (Basel, Switzerland)·2024
Same author

The use of probiotics and prebiotics in decolonizing pathogenic bacteria from the gut; a systematic review and meta-analysis of clinical outcomes.

Gut microbes·2024

Related Experiment Video

Updated: Dec 20, 2025

Grafting Multiwalled Carbon Nanotubes with Polystyrene to Enable Self-Assembly and Anisotropic Patchiness
11:09

Grafting Multiwalled Carbon Nanotubes with Polystyrene to Enable Self-Assembly and Anisotropic Patchiness

Published on: April 1, 2018

8.4K

Bio-based hyperbranched poly(ester amide)-MWCNT nanocomposites: multimodalities at the biointerface.

Sujata Pramanik1, Rocktotpal Konwarh, Nilakshi Barua

  • 1Department of Chemical Sciences, Tezpur University, Tezpur-784028, India. karakniranjan@yahoo.com.

Biomaterials Science
|June 3, 2020
PubMed
Summary

New bio-based nanocomposites combining hyperbranched poly(ester amide) and functionalized multiwalled carbon nanotubes show promising antibacterial activity and biocompatibility. These materials offer potential for antimicrobial wound dressings.

More Related Videos

Advanced Compositional Analysis of Nanoparticle-polymer Composites Using Direct Fluorescence Imaging
07:41

Advanced Compositional Analysis of Nanoparticle-polymer Composites Using Direct Fluorescence Imaging

Published on: July 19, 2016

8.0K
Environmentally-controlled Microtensile Testing of Mechanically-adaptive Polymer Nanocomposites for ex vivo Characterization
11:38

Environmentally-controlled Microtensile Testing of Mechanically-adaptive Polymer Nanocomposites for ex vivo Characterization

Published on: August 20, 2013

10.5K

Related Experiment Videos

Last Updated: Dec 20, 2025

Grafting Multiwalled Carbon Nanotubes with Polystyrene to Enable Self-Assembly and Anisotropic Patchiness
11:09

Grafting Multiwalled Carbon Nanotubes with Polystyrene to Enable Self-Assembly and Anisotropic Patchiness

Published on: April 1, 2018

8.4K
Advanced Compositional Analysis of Nanoparticle-polymer Composites Using Direct Fluorescence Imaging
07:41

Advanced Compositional Analysis of Nanoparticle-polymer Composites Using Direct Fluorescence Imaging

Published on: July 19, 2016

8.0K
Environmentally-controlled Microtensile Testing of Mechanically-adaptive Polymer Nanocomposites for ex vivo Characterization
11:38

Environmentally-controlled Microtensile Testing of Mechanically-adaptive Polymer Nanocomposites for ex vivo Characterization

Published on: August 20, 2013

10.5K

Area of Science:

  • Biomaterials Science
  • Nanotechnology
  • Polymer Chemistry

Background:

  • Growing demand for biocompatible, biodegradable nanomaterials with antibacterial properties, especially against resistant bacteria.
  • Need for advanced materials at the biointerface to address multiple biological functions.
  • Interest in carbon nanotube-based nanocomposites for biomedical applications.

Purpose of the Study:

  • To fabricate and characterize novel hyperbranched poly(ester amide) (HBPEA)-microwave functionalized multiwalled carbon nanotube (f-MWCNT) nanocomposites.
  • To evaluate the biocompatibility and antibacterial efficacy of these nanocomposites.
  • To explore their potential as antimicrobial dressing materials.

Main Methods:

  • Ex situ polymerization technique to incorporate f-MWCNTs (1, 2.5, 5 wt%) into HBPEA.
  • Fourier transform infrared spectroscopy (FTIR) for structural analysis.
  • Mechanical property testing, in vitro cell adhesion and proliferation assays (PBMC).
  • Antibacterial activity assessment (CFU count, protein concentration) against Gram-positive and Gram-negative bacteria.
  • Microscopic analysis (SEM) and UV-visible spectroscopy for cell damage validation.

Main Results:

  • Successful fabrication of thermosetting nanocomposites with enhanced mechanical properties (~170%).
  • Demonstrated biocompatibility with peripheral blood mononuclear cells (PBMC), with increased viability at higher f-MWCNT content.
  • Significant antibacterial activity, particularly against Gram-positive bacteria and Mycobacterium smegmatis.
  • Validation of bacterial cell damage via spectroscopy and SEM.
  • Characterization of microporous structures with specific pore diameters and porosity.

Conclusions:

  • The developed HBPEA-f-MWCNT nanocomposites exhibit a favorable combination of biocompatibility and potent antibacterial activity.
  • These materials show potential for long-term antimicrobial effects and biocompatibility with human cells.
  • The nanocomposites are promising candidates for biomedical applications, especially as antimicrobial wound dressings for infected wounds.