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Updated: Dec 20, 2025

Isolation, Characterization, and Therapeutic Application of Extracellular Vesicles from Cultured Human Mesenchymal Stem Cells
Published on: September 23, 2022
Extracellular vesicles derived from different sources of mesenchymal stem cells: therapeutic effects and
Jiaxin Cai1,2,3, Junyong Wu1,2,3, Jiemin Wang1,2,3
11Department of Pharmacy, The Second Xiangya Hospital, Central South University, Furong District, Changsha, Hunan China.
Abstract:
Mesenchymal stem cells (MSCs) were known to have excellent properties in cell therapy. However, the risk of immune rejection associated with cell transplant therapy hampers its use. Extracellular vesicles secreted by MSCs derived from different sources that contain therapeutic molecules such as RNA and proteins, which is a novel strategy for cell-free therapy. Recently, researches show EVs from MSCs (MSC-EVs) of different sources have special functions and effects on different diseases. Here, we collected these researches and compared them to each other. In addition, their potential and possible application in clinical treatment are described.
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