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Updated: Dec 20, 2025

High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents HPHC
Published on: May 10, 2016
Enabling health information exchange at a US Poison Control Center.
Mollie R Cummins1, Guilherme Del Fiol2, Barbara I Crouch3
1University of Utah College of Nursing, Salt Lake City, Utah, USA.
Poison control centers can now participate in health information exchange (HIE) using the new SNOWHITE software and adapted C-CDA standards. This breakthrough enables seamless data sharing for improved public health.
Area of Science:
- Health Informatics
- Public Health
- Clinical Informatics
Background:
- Poison control centers (PCCs) were previously unable to participate in standards-based health information exchange (HIE).
- Barriers included noncompliant software, lack of informatics infrastructure, and workflow integration challenges.
Purpose of the Study:
- To enable PCCs to participate in standards-based HIE.
- To overcome existing technological and workflow barriers for PCCs.
Main Methods:
- Adapted Health Level Seven Consolidated Clinical Document Architecture (C-CDA) consultation note for PCC use.
- Developed SNOWHITE software for PCC HIE integration.
- Utilized rapid prototyping to define HIE dashboard requirements.
Main Results:
- Successfully implemented HIE process and SNOWHITE software at the Utah PCC.
- Initiated outbound C-CDA transmissions in February 2017.
- Began receiving inbound C-CDAs in October 2018.
Conclusions:
- Achieved the first participation of PCCs in standards-based HIE in the US.
- Developed a viable process and informatics tools for PCC HIE.
- Identified challenges in patient identification, workflow integration, and software development for future improvements.
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