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Association between benign paroxysmal positional vertigo and osteoporosis: two nested case-control studies.
1Department of Otorhinolaryngology-Head & Neck Surgery, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea.
Summary
This study reveals a two-way link between osteoporosis and benign paroxysmal positional vertigo (BPPV). Osteoporosis increases BPPV risk, while BPPV also elevates osteoporosis risk, particularly in women.
Area of Science:
- Geriatrics
- Neurology
- Orthopedics
Background:
- Previous research suggested a link between osteoporosis and benign paroxysmal positional vertigo (BPPV).
- This study investigated the bidirectional association between these two conditions.
Purpose of the Study:
- To determine if osteoporosis increases the risk of BPPV.
- To ascertain if BPPV increases the risk of osteoporosis.
- To explore the reciprocal relationship between BPPV and osteoporosis.
Main Methods:
- Utilized Korean National Health Insurance Service-Health Screening Cohort data (2002-2013).
- Study I: Matched 50,897 osteoporosis patients with controls for BPPV history.
- Study II: Matched 9,621 BPPV patients with controls for osteoporosis history.
- Subgroup analyses were performed based on age and sex.
Main Results:
- Osteoporosis patients had a 1.28 times higher likelihood of developing BPPV.
- BPPV patients had a 1.34 times higher likelihood of having osteoporosis.
- This bidirectional association was significant in women.
Conclusions:
- A significant bidirectional relationship exists between osteoporosis and BPPV.
- Osteoporosis is associated with an increased risk of BPPV.
- BPPV is associated with an increased risk of osteoporosis, especially in women.
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