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Updated: Dec 20, 2025
Imaging CD4 T Cell Interstitial Migration in the Inflamed Dermis
Published on: March 25, 2016
A case of cutaneous extranodal natural killer/T-cell lymphoma clinically and histopathologically mimicking interface
Myoung Eun Choi1, Hee Joo Yang1, Woo Jin Lee1
1Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Abstract:
Extranodal natural killer/T-cell lymphoma (ENKTL) is a rare but aggressive cancer characterised by angiocentric and angiodestructive infiltration by NK-cells, or cytotoxic T-cell types. Histopathologically, ENKTL shows a multinodular or diffuse infiltration localised to vascular structures, resulting in angiodestruction and necrosis. We present a patient with an initially suspected diagnosis of benign interface dermatitis with a differential diagnosis of mycosis fungoides that was later found to be an aggressive extranodal natural killer/T-cell lymphoma of a nasal type and with a dismal prognosis.
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