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Biopharmaceutics and Pharmacokinetics: Overview01:28

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Understanding drugs, drug products, and their performance in pharmaceutical science is pivotal. Drugs, whether simple molecules or complex compounds, are designed to interact with the body's biological systems to diagnose, treat, or prevent diseases. Drug products include various delivery systems such as tablets, capsules, injections, and inhalers. The performance of these drug products is gauged by their ability to deliver the active ingredient to the desired site of action at the...
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Pharmaceutical products contain more than just the active drug; they also contain various excipients such as binders, solubilizers, stabilizers, preservatives, and other elements. In some cases, impurities or contaminants might be present. Traditionally, quality control in pharmaceuticals has primarily focused on the analysis of the active drug, often overlooking the impact of these additional components. The recent issue with heparin contamination by over-sulfated chondroitin sulfate, a...
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As defined by regulatory standards, pharmaceutical equivalents require generic drug products to have identical dosage forms and chemically identical active pharmaceutical ingredients (APIs). They must adhere to compendial or applicable standards for potency, content uniformity, disintegration times, and dissolution rates. In the case of modified-release dosage forms, variations in drug content are permissible as long as the delivered amount remains consistent with the innovator drug product.
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A Simple Fractionated Extraction Method for the Comprehensive Analysis of Metabolites, Lipids, and Proteins from a Single Sample
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And What About the Pharmacist?

Martin Buijsen, Wilma Göttgens

    Cambridge Quarterly of Healthcare Ethics : CQ : the International Journal of Healthcare Ethics Committees
    |June 3, 2020
    PubMed
    Summary

    Dutch law decriminalizes euthanasia, but pharmacists

    Area of Science:

    • Medical Law
    • Pharmaceutical Practice
    • Bioethics

    Background:

    • Euthanasia and assisted suicide are decriminalized in the Netherlands under specific conditions.
    • Physicians performing euthanasia must adhere to the due care requirements outlined in the Euthanasia Act.
    • Pharmacists play a crucial role in the medical procedure of euthanasia, supplying necessary medications.

    Purpose of the Study:

    • To examine the legal and professional responsibilities of pharmacists in the context of euthanasia in the Netherlands.
    • To identify the inadequacy of current professional rules for pharmacists regarding euthanasia.
    • To highlight the need for clear legal guidelines for pharmacists involved in euthanasia.

    Main Methods:

    • Analysis of Dutch legislation pertaining to euthanasia and assisted suicide.
    Keywords:
    euthanasialethal drugspharmacistphysician-assisted suicideprofessional rulesprofessional standardtermination of life on request

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  • Review of existing professional rules and guidelines for pharmacists in the Netherlands.
  • Identification of legal and practical challenges faced by pharmacists in euthanasia cases.

    • Main Results:

    • Pharmacists' responsibilities concerning euthanasia are not explicitly defined in Dutch law.
    • Current professional rules for pharmacists do not provide sufficient guidance for euthanasia-related issues.
    • This legal ambiguity can lead to challenges in ensuring due medical care during euthanasia.

    Conclusions:

    • There is a significant gap in the legal framework regarding the role of pharmacists in euthanasia.
    • Updated legislation or clear professional guidelines are necessary to address the responsibilities of pharmacists in euthanasia.
    • Ensuring adequate legal and professional support for pharmacists is essential for the proper execution of euthanasia.