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Two water-soluble fluorescence probes based on 5(6)-carboxyl rhodamine for Cu2+ imaging in living cells

Mengyao Zhang1, Jun Wang1, Ting Jia1

  • 1College of Chemistry and Materials Science, Fujian Normal University, Fuzhou, China.

Luminescence : the Journal of Biological and Chemical Luminescence
|June 3, 2020
PubMed

Keywords:
5(6)-carboxyl rhodamineCu2+fluorescence proberegioselective esterification

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Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...