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Multidisciplinary approach to the therapy of chronic sinusitis
D Bassetti1, E Concia, M Solbiati
1Faculty of Medicine and Surgery, University of Verona, Italy.
Drugs Under Experimental and Clinical Research
|January 1, 1988
Abstract:
Twenty patients with maxillary sinusitis were treated with cefotetan (1 g, i.m.) twice a day. Samples of blood and maxillary sinus mucous membrane were taken in eight patients 2 h after dosing during the third day of therapy to evaluate drug concentration. Results show the excellent clinical and bacteriological effectiveness of cefotetan, as well as its high tissue penetration.