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Updated: Dec 20, 2025

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
Published on: December 11, 2017
Clinical presentation and outcomes of adults with bicuspid aortic valves: 2020 update
Li-Tan Yang1, Christophe Tribouilloy2, Ahmad Masri3
1Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
Insights
Bicuspid aortic valve (BAV) patients with typical presentations have normal survival if complications are treated. Complex BAV presentations or late diagnosis may lead to reduced survival, highlighting research needs.
Area of Science:
- Cardiology
- Genetics
- Vascular Biology
Background:
- Congenital bicuspid aortic valve (BAV) is a complex condition with varied presentations.
- Understanding these presentations is key to managing BAV-related valvulo-aortopathy.
- BAV affects aortic valve structure and the aorta itself.
Purpose of the Study:
- To review the different presentations of BAV valvulo-aortopathy.
- To elucidate the burden of BAV-related complications in typical presentations.
- To discuss survival implications for various BAV patient groups.
Main Methods:
- Literature review of BAV presentations and outcomes.
- Analysis of complication data in typical BAV presentations.
- Discussion of survival data comparing BAV patients to the general population.
Main Results:
- Typical BAV presentations, when managed promptly, allow for normal long-term survival.
- Serious complications like endocarditis and dissection are infrequent in BAV.
- Complex BAV presentations or delayed care can result in a survival penalty.
Conclusions:
- Timely identification and treatment of complications are crucial for BAV patients with typical presentations.
- Further research into preventing and treating common BAV complications like valve dysfunction and aortic dilation is needed.
- BAV patients with complex presentations or delayed care require specialized management strategies to mitigate survival risks.
Abstract:
The congenital bicuspid aortic valve (BAV) is a heterogeneous condition that is better understood considering 3 types of valvulo-aortopathy presentations: A typical-presentation valvulo-aortopathy, a complex-presentation valvulo-aortopathy and an uncomplicated/undiagnosed-presentation. The burden of BAV-related complications has been elucidated in patients with the typical-presentation valvulo-aortopathy and is discussed in this review. These patients enjoy an overall normal expected long-term survival as long as complications are identified and treated in a timely manner. This notion and the fact that the most dreaded complications (infective endocarditis and aortic dissection) are infrequent, represent important reassuring points for the BAV patient. Common complications such as valve dysfunction and aorta dilatation must be the subject of focused research in prevention and treatment. Conversely, BAV patients with complex-presentation valvulo-artopathy, as well as typical valvulo-aortopathy BAV patients who are older, with advanced valvular dysfunction, and possible late-referral to specialized care, may incur a survival penalty as compared to the general population. An evidence-based discussion of these concepts is provided in this review.
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