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Stabilization of BMIz Score is Associated with a Decrease in Visceral Fat in Children with Obesity.

Yashoda Naik1, David B Allen1, Jens Eickhoff2

  • 1Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.

Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme
|June 3, 2020
PubMed
Summary
This summary is machine-generated.

Preventing an increase in Body Mass Index z-score (BMIz) in obese children significantly reduces visceral fat and improves cardiovascular fitness (CVF), even without changes in total body fat. Maintaining a stable BMIz is a key initial goal for improving health outcomes.

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Area of Science:

  • Pediatrics
  • Obesity Research
  • Cardiovascular Health

Background:

  • Body Mass Index z-score (BMIz) is a standard metric for assessing childhood obesity.
  • The relationship between BMIz score changes and visceral fat changes in children is not well-established.
  • Lifestyle interventions are crucial for managing childhood obesity.

Purpose of the Study:

  • To investigate changes in visceral fat, cardiovascular fitness (CVF), and metabolic health over six months.
  • To compare outcomes between children with stable/decreased BMIz versus those with increased BMIz.

Main Methods:

  • Ninety children with obesity underwent a 6-month lifestyle intervention.
  • Assessments included dual X-ray absorptiometry (DXA) for body fat, sub-maximal VO2 for CVF, and metabolic markers.
  • Children were grouped based on BMIz change: stable/decreased vs. increased.

Main Results:

  • The stable/decreased BMIz group showed a significant reduction in visceral fat (-258±650 g) compared to the increased BMIz group (+137±528 g).
  • Cardiovascular fitness (CVF) significantly increased in the stable/decreased BMIz group (+1.2 ml/kg/min), but not in the increased BMIz group.
  • No significant changes in total body fat or metabolic markers were observed between groups.

Conclusions:

  • Preventing BMIz increase in obese children is associated with significant visceral fat reduction and improved CVF, independent of total body fat changes.
  • Achieving stable BMIz and enhancing fitness are critical initial targets in lifestyle interventions for obese children.
  • These findings highlight the importance of BMIz management for improving cardiovascular and metabolic health in pediatric obesity.