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Multiple calcifying hyperplastic dental follicles: a major diagnostic consideration in multiple pericoronal lesions -
Israel Guardado-Luevanos1, Anna Jazmine Haro2, Marisol Godínez-Rubí2
1Master's Program in Oral Pathology and Medicine, Department of Integral Dental Clinics, University Centre of Health Sciences, Universidad de Guadalajara, Sierra Mojada No. 950, Col. Independencia, C.P. 44340, Guadalajara, Jalisco, Mexico.
Background:
Pericoronal radiolucent lesions are a common radiographic finding, but it is rare that they occur in multiple forms. Multiple calcifying hyperplastic dental follicles (MCHDF) are entities with few cases described to date; nevertheless, they appear to have a very particular phenotypic pattern.
Cases Presentation:
Case 1: A 10-year-old male was evaluated radiographically, revealing four impacted canines, each accompanied by unilocular pericoronal radiolucency. Case 2: A 16-year-old male was planning orthodontic treatment; following his radiological evaluation all third molars were found to be accompanied with pericoronal radiolucencies. Enucleation, and third molar removal along with the pericoronal tissue were the respective treatments. Microscopically, in both cases, the specimens shown odontogenic epithelium, and type I and II calcifications in the hyperplastic follicles, all these characteristics were consistent with MCHDF.
Conclusion:
Although MCHDF are a rare entity, they must be considered in the differential diagnosis of multiple pericoronal lesions. Under the light of the current evidence, the histological findings may be relatively heterogeneous, but their integration with both the clinical data, which are apparently particular, and with the radiographic characteristics, can lead to a definitive diagnosis.
