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Updated: Dec 19, 2025

Capillary Electrophoresis-based Hydrogen/Deuterium Exchange for Conformational Characterization of Proteins with Top-down Mass Spectrometry
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Complementarity of Hydrogen/Deuterium Exchange Mass Spectrometry and Cryo-Electron Microscopy

John R Engen1, Elizabeth A Komives2

  • 1Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA 02115, USA.

Trends in Biochemical Sciences
|June 4, 2020
PubMed

Keywords:
HDX-MScryo-EMprotein conformationstructural heterogeneity

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