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Lipid Control Post Coronary Artery Bypass Graft: One Year Follow-Up of a Middle-Eastern Cohort
Bassam Atallah1,2, Ramzi Khaddage3, Ziad G Sadik1
1Cleveland Clinic Abu Dhabi, Department of Pharmacy Services, Al Maryah Island, Abu Dhabi, AE.
Insights
Lipid management after coronary artery bypass graft surgery (CABG) in the Middle East shows gaps in follow-up and goal achievement. New guidelines require updated provider practices for high-risk cardiovascular patients.
Area of Science:
- Cardiology
- Public Health
- Clinical Practice Guidelines
Background:
- Limited data exists on patient characteristics and lipid management post-guideline updates in Middle Eastern secondary prevention patients.
- Coronary artery bypass graft surgery (CABG) patients represent a critical secondary prevention cohort.
Purpose of the Study:
- To investigate patient demographics, comorbidities, and lipid-lowering medication use.
- To assess lipid management practices in secondary prevention patients up to one year post-CABG, aligned with current cholesterol guidelines.
Main Methods:
- Retrospective chart review of 189 patients discharged post-CABG between February 2017 and February 2018.
- Analysis of baseline characteristics, comorbidities, lipid-lowering therapies, and follow-up care including lipid panels.
Main Results:
- Most patients were classified as very high or extremely high risk (ACC/AHA and AACE guidelines).
- While 93.1% were discharged on high-intensity statins, only 44.4% had follow-up beyond 3 months, and 51.2% of those had lipid panels checked.
- Among patients with follow-up lipid panels, 59.3% achieved LDL <70 mg/dL and 29% achieved LDL <55 mg/dL.
Conclusions:
- Patients undergoing CABG in this Middle Eastern center are high-risk for atherosclerotic cardiovascular disease (ASCVD).
- Lipid goals are frequently unmet, and monitoring is inconsistent, highlighting a need for adherence to recent guidelines.
- A shift from older risk stratification and statin-only approaches to newer guideline recommendations is necessary for providers.
Background:
Data on patient characteristics and provider practices in the management of lipids per the new guidelines in specific secondary prevention patients in the Middle East is limited.
Objective:
To explore patient characteristics and lipid management practices according to the new cholesterol guidelines in secondary prevention patients, up to one year following discharge for coronary artery bypass graft surgery (CABG).
Methods:
A retrospective chart review of patients discharged post CABG between February 2017 and February 2018 at a quaternary care centre in the Middle East. Patients were characterized by baseline demographics, comorbidities, and use of lipid lowering medications.
Results:
189 patients were included in the analysis. Most were diabetic (70.9%) and classified as very high risk per the ACC/AHA guidelines (84.1%) and as extremely high risk per the AACE guidelines (85.2%). Most patients (93.1%) were discharged on high intensity statin. About one third (28.6%) were never seen or only followed once within the first 2 weeks post discharge. Of those who continued to follow up beyond 3 months and within 1 year of discharge (44.4%), about half (51.2%) had follow-up lipid panels performed. Patients who followed up and were seen by a cardiologist were five times more likely to have lipid panels ordered than those seen solely by a CT surgeon. Of those with follow-up lipid panels beyond 3 months: 59.3% achieved LDL goal of <70 mg/dL and 29% achieved LDL <55 mg/dL based on their respective goals.
Conclusions:
Most patients undergoing CABG in a quaternary care centre in the Middle East are high risk ASCVD. Nonetheless, lipid goals are not commonly achieved nor routinely monitored. Providers will need to transition from the previous risk stratification and statin-only focused approach to adopt the most recent guidelines.
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