Related Experiment Video
Updated: Dec 19, 2025

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291
Published on: December 10, 2016
Clostridioides difficile co-infection with Enterohemorrhagic Escherichia coli (EHEC)-a potentially fatal combination
Farah Deshmukh1, Upasana Agrawal2, Nancy Merrell3
1Department of Internal Medicine, Bassett Medical Center and Columbia University College of Physicians and Surgeons, New York, USA.
Abstract:
There has been a significant increase in hospital and community acquired Clostridioides difficile infection in the past decade. In addition to CDI, the rate of infection with enterohemorrhagic Escherichia coli (EHEC) has also increased by 28% in United States in the last five years. Concomitant CDI and EHEC infections are rare and if not identified early such co-infections can be fatal. We present the case of patient with hematochezia who was found to be positive for Clostridioides difficile and EHEC. She had a complicated hospital course that required timely identification of complications and management.
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