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The Effect of Coronavirus Disease 2019 on Cardiovascular Diseases

Lutfu Askin1, Okan Tanrıverdi1, Husna Sengul Askin2

  • 1Adiyaman Universitesi Egitim ve Arastirma Hastanesi - Cardiology,Adıyaman, Centry - Turquia.

Arquivos Brasileiros De Cardiologia
|June 4, 2020
PubMed

Insights

Coronavirus disease 2019 (COVID-19) impacts the cardiovascular system, potentially causing myocarditis. Research is ongoing regarding ACE inhibitors and ARBs in COVID-19 patients with heart conditions.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Pharmacology

Background:

  • COVID-19 pandemic affects over 1.3 million patients globally.
  • The virus utilizes the ACE2 receptor, impacting cardiovascular health.
  • Cardiovascular comorbidities are prevalent in COVID-19 cases.

Purpose of the Study:

  • To investigate the role of ACE2 in COVID-19 pathogenesis.
  • To examine the incidence of myocarditis in COVID-19 patients.
  • To evaluate the implications of ACE inhibitors and ARBs in COVID-19 management.

Main Methods:

  • Review of current literature on COVID-19 and cardiovascular complications.
  • Analysis of patient data regarding comorbidities and treatment.
  • Assessment of the mechanism of viral entry via ACE2.

Main Results:

  • Myocarditis affects approximately 10% of COVID-19 cases, rising to 22% in critical patients.
  • Cardiovascular comorbidities are frequently observed.
  • The role of ACE inhibitors and ARBs requires further investigation.

Conclusions:

  • COVID-19 poses significant cardiovascular risks, including myocarditis.
  • The management of hypertension and heart failure medications (ACE inhibitors, ARBs) in COVID-19 patients needs clarification.
  • Continued research is crucial for effective COVID-19 treatment and prevention strategies.

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