Association Between Exposure to Ambient Air Pollution and Thyroid Function in Korean Adults
Hyun-Jin Kim1, Hyuktae Kwon2, Jae Moon Yun2
1National Cancer Control Institute, National Cancer Center, Goyang, South Korea.
The Journal of Clinical Endocrinology and Metabolism
|June 4, 2020
Summary
Air pollution, including nitrogen dioxide and carbon monoxide, is linked to altered thyroid function (TSH and FT4) in the general population. These effects are more pronounced in older adults and those who are overweight or obese.
Area of Science:
- Environmental Health
- Endocrinology
- Public Health
Background:
- Limited studies have explored the link between air pollution and thyroid function in general populations.
- Previous research focused on smaller samples or specific regions.
Purpose of the Study:
- To investigate the association between air pollution exposure and thyroid function in a nationwide sample of Korean adults.
- To examine if this association differs across age and body mass index (BMI) subgroups.
Main Methods:
- Analysis of 4704 Korean adults using annual average exposure data for PM10, NO2, SO2, and CO.
- Measurement of serum TSH and FT4 concentrations as thyroid function indicators.
- Stratification by age and BMI to assess subgroup differences.
Main Results:
- Exposure to NO2 and CO was significantly associated with elevated TSH and reduced FT4.
- In men, PM10 exposure also showed a positive association with TSH.
- Stronger effects of NO2 and CO were observed in older adults and individuals with overweight or obesity.
Conclusions:
- This study establishes a link between air pollution exposure and thyroid function in the general population.
- The association between air pollution and thyroid function is potentially stronger in older, overweight, or obese adults.
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