Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Assessment of Diffusion and Perfusion01:17

Assessment of Diffusion and Perfusion

1.4K
Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this...
1.4K
Errors occurring during blood pressure monitoring01:25

Errors occurring during blood pressure monitoring

1.2K
Blood pressure monitoring is a crucial clinical procedure in diagnosing and managing various cardiovascular conditions. Despite its significance, the accuracy of blood pressure measurements can be compromised by multiple factors, potentially leading to either falsely high or low readings. These inaccuracies are critical as they can significantly impact patient care. So, it is vital to understand these challenges deeply and adopt strategic approaches to minimize errors.
Several factors...
1.2K
Measurement of Blood Pressure01:17

Measurement of Blood Pressure

2.4K
Assessing blood pressure is a standard procedure executed in virtually all medical environments. The method utilized today was established over a hundred years ago by an innovative Russian doctor, Dr. Nikolai Korotkoff. The soft ticking noise, known as Korotkoff sounds, heard while taking blood pressure readings results from turbulent blood flow within the vessels. The apparatus required for this procedure includes a sphygmomanometer, a blood pressure cuff attached to a gauge, and a...
2.4K
Acute Respiratory Failure-III01:30

Acute Respiratory Failure-III

647
Hypercapnic respiratory failure, also known as Type 2 or ventilatory respiratory failure, is a severe condition characterized by the body's inability to effectively remove carbon dioxide (CO2) from the bloodstream. It leads to an arterial CO2 pressure (PaCO2) exceeding 45 mmHg and a blood pH above 7.35. This situation indicates that the body's ventilatory demand, or the ventilation needed to maintain normal PaCO2 levels, surpasses its supply or the maximum gas flow achievable without...
647
Endoscopic Studies II: Thoracocentesis01:26

Endoscopic Studies II: Thoracocentesis

1.1K
Thoracentesis(Thoracocentesis), commonly known as pleural tap, is a medical procedure where a 22 gauge needle is inserted into the pleural space, the area between the lung and chest wall. This procedure is commonly performed to diagnose or treat various respiratory disorders.
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
1.1K
Assessment of Ventilation I: Respiratory Rate01:20

Assessment of Ventilation I: Respiratory Rate

1.8K
Assessment of Ventilation
A Ventilation assessment is critical for monitoring a patient's health status. Respiration, one of the most accessible vital signs, provides insights into the function of numerous body systems and can indicate serious health issues, such as brainstem injuries from head trauma.
Critical Guidelines for Assessing Ventilation:
1.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Accurate heat currents via reorganized master equation.

Physical review. E·2025
Same author

Virological characterization of a new isolated strain of Andes virus involved in the recent person-to-person transmission outbreak reported in Argentina.

PLoS neglected tropical diseases·2025
Same author

Unmasking Neuroendocrine Prostate Cancer with a Machine Learning-Driven 7-Gene Stemness Signature that Predicts Progression.

medRxiv : the preprint server for health sciences·2024
Same author

Could alternative pathways for carotenoid transformation affect colour production efficiency? A correlative study in wild common crossbills (Loxia curvirostra).

Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology·2024
Same author

Standardisation facilitates reliable interpretation of ETCO<sub>2</sub> during manual cardiopulmonary resuscitation.

Resuscitation·2024
Same author

Metrics of impulsiveness of manual chest compressions for out-of-hospital cardiopulmonary resuscitation.

Heliyon·2024

Related Experiment Video

Updated: Dec 19, 2025

Expired CO2 Measurement in Intubated or Spontaneously Breathing Patients from the Emergency Department
07:52

Expired CO2 Measurement in Intubated or Spontaneously Breathing Patients from the Emergency Department

Published on: January 29, 2011

16.7K

Chest compressions induce errors in end-tidal carbon dioxide measurement.

Mikel Leturiondo1, Sofía Ruiz de Gauna1, José Julio Gutiérrez1

  • 1University of the Basque Country, UPV/EHU, Bilbao, Bizkaia, Spain.

Resuscitation
|June 4, 2020
PubMed
Summary

Chest compressions during CPR can distort end-tidal carbon dioxide (ETCO2) measurements, impacting accuracy. This study found significant errors in ETCO2 readings when capnograms were affected by chest compression artifacts.

Keywords:
Advanced life supportCapnometryCardiopulmonary resuscitationChest compressionsEnd-tidal CO2VentilationsWaveform capnography

More Related Videos

Evaluation of Capnography Sampling Line Compatibility and Accuracy when Used with a Portable Capnography Monitor
07:51

Evaluation of Capnography Sampling Line Compatibility and Accuracy when Used with a Portable Capnography Monitor

Published on: September 29, 2020

9.4K
Combining Volumetric Capnography And Barometric Plethysmography To Measure The Lung Structure-function Relationship
08:25

Combining Volumetric Capnography And Barometric Plethysmography To Measure The Lung Structure-function Relationship

Published on: January 8, 2019

9.8K

Related Experiment Videos

Last Updated: Dec 19, 2025

Expired CO2 Measurement in Intubated or Spontaneously Breathing Patients from the Emergency Department
07:52

Expired CO2 Measurement in Intubated or Spontaneously Breathing Patients from the Emergency Department

Published on: January 29, 2011

16.7K
Evaluation of Capnography Sampling Line Compatibility and Accuracy when Used with a Portable Capnography Monitor
07:51

Evaluation of Capnography Sampling Line Compatibility and Accuracy when Used with a Portable Capnography Monitor

Published on: September 29, 2020

9.4K
Combining Volumetric Capnography And Barometric Plethysmography To Measure The Lung Structure-function Relationship
08:25

Combining Volumetric Capnography And Barometric Plethysmography To Measure The Lung Structure-function Relationship

Published on: January 8, 2019

9.8K

Area of Science:

  • Emergency Medicine
  • Physiology
  • Medical Device Technology

Background:

  • End-tidal carbon dioxide (ETCO2) is a key non-invasive indicator of cardiac output and perfusion during cardiopulmonary resuscitation (CPR).
  • Chest compressions (CCs) during CPR can introduce artifacts into capnograms, potentially compromising the accuracy of ETCO2 measurements.
  • The reliability of ETCO2 monitoring during out-of-hospital manual CPR requires evaluation in the context of these artifacts.

Purpose of the Study:

  • To quantify the impact of chest compression (CC) artifacts on the accuracy of end-tidal carbon dioxide (ETCO2) measurements during out-of-hospital manual CPR.
  • To assess the performance of different capnometry devices in the presence of CC-induced artifacts.
  • To determine the extent of ETCO2 measurement errors attributable to CC artifacts.

Main Methods:

  • Retrospective analysis of monitor-defibrillator recordings from two advanced life support agencies during out-of-hospital cardiac arrest.
  • Manual annotation of ventilations within 1-minute capnogram segments, identifying those distorted by CC artifacts.
  • Comparison of manually annotated ETCO2 values with stored capnometry data to calculate measurement errors.

Main Results:

  • Analysis of 407 segments (65 patients) revealed a significant increase in median unsigned ETCO2 error for distorted ventilations (5.5 IQR 1.8-14.1%) compared to non-distorted ones (1.5 IQR 0.6-3.1%).
  • Errors exceeding 10 mmHg occurred in 9% and exceeding 15 mmHg in 5% of distorted ventilations across both agencies.
  • Specific error rates varied between agencies, with agency B showing higher median errors for distorted ventilations (8.3 IQR 3.9-19.5%) than agency A (3.7 IQR 1.0-9.9%).

Conclusions:

  • Chest compression artifacts demonstrably introduce significant errors into ETCO2 measurements during CPR.
  • Current capnometer algorithms may require adaptation to ensure reliable ETCO2 readings in the presence of CC artifacts.
  • The findings highlight the need for improved artifact detection and correction in capnography devices used during resuscitation efforts.