Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

In Vitro Drug Dissolution: Compendial Testing Models II01:09

In Vitro Drug Dissolution: Compendial Testing Models II

151
Various dissolution methods are utilized to assess a drug’s dissolution rate, including the flow-through cell, paddle-over-disk, cylinder, and reciprocating disk methods.The flow-through cell apparatus (USP (United States Pharmacopeia) method 4) comprises a reservoir for the dissolution medium and a pump that propels the medium through the cell containing the test sample. This method is crucial for assessing modified-release dosage forms with minimally soluble active ingredients,...
151
In Vitro Drug Dissolution: Compendial Testing Models I01:13

In Vitro Drug Dissolution: Compendial Testing Models I

150
Compendial dissolution methods are standardized procedures defined by pharmacopeias to evaluate the rate at which a drug dissolves in a specific medium. These methods ensure batch-to-batch consistency, enable quality control, and support the prediction of drug bioavailability. They are critical for both immediate and modified-release drug products.The apparatuses used for dissolution testing differ in their design and mechanical function, but all aim to simulate the physiological environment of...
150
Three-Compartment Open Model01:06

Three-Compartment Open Model

752
The three-compartment open model is a pharmacokinetic model used to describe the distribution and elimination of drugs following extravascular administration. It comprises a central compartment representing the plasma and two peripheral compartments. The highly perfused peripheral compartment represents organs and tissues with a rich blood supply, such as the liver, kidneys, and lungs. The scarcely perfused peripheral compartment represents tissues with lower blood supply, such as adipose...
752

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Phenomenology of the Chromic Response in Transition-Metal Oxides.

Materials (Basel, Switzerland)·2026
Same author

From LQ to AI-BED-Fx: A Unified Multi-Fraction Radiobiological and Machine-Learning Framework for Gamma Knife Radiosurgery Across Intracranial Pathologies.

Cancers·2026
Same author

Life as Counterfactual Geometry: An Adversarial Theory of Biological Function.

Entropy (Basel, Switzerland)·2026
Same author

Conifer Bark Extracts as Modulators of Endothelial Function: Evidence from <i>Abies alba</i> and <i>Cedrus brevifolia</i>.

Plants (Basel, Switzerland)·2026
Same author

Evaluating the Managerial Feasibility of an AI-Based Tooth-Percussion Signal Screening Concept for Dental Caries: An In Silico Study.

Diagnostics (Basel, Switzerland)·2026
Same author

Complex Fluids in a Multifractal Space: Scale Covariance and the Emergence of the Fractal Force.

Entropy (Basel, Switzerland)·2026

Related Experiment Video

Updated: Dec 19, 2025

A Freeze-Thawing Method to Prepare Chitosan-Polyvinyl alcohol Hydrogels Without Crosslinking Agents and Diflunisal Release Studies
08:59

A Freeze-Thawing Method to Prepare Chitosan-Polyvinyl alcohol Hydrogels Without Crosslinking Agents and Diflunisal Release Studies

Published on: January 14, 2020

18.7K

A Theoretical Multifractal Model for Assessing Urea Release from Chitosan Based Formulations.

Manuela Maria Iftime1, Stefan Andrei Irimiciuc2, Maricel Agop3

  • 1Romanian Academy of Sciences, Petru Poni Institute of Macromolecular Chemistry, 41A Grigore Ghica Voda Alley, 700487 Iasi, Romania.

Polymers
|June 5, 2020
PubMed
Summary

This study calibrates a multifractal model using soil conditioner data for urea release. The validated model accurately predicts fertilizer release, improving agricultural soil management.

Keywords:
chitosanmultifractal theoretical modelmultifunctional materials

More Related Videos

Preparation of Expanded Chitin Foams and their Use in the Removal of Aqueous Copper
06:36

Preparation of Expanded Chitin Foams and their Use in the Removal of Aqueous Copper

Published on: February 27, 2021

4.0K
Fabrication of Size-Controlled and Emulsion-Free Chitosan-Genipin Microgels for Tissue Engineering Applications
05:26

Fabrication of Size-Controlled and Emulsion-Free Chitosan-Genipin Microgels for Tissue Engineering Applications

Published on: April 13, 2022

3.8K

Related Experiment Videos

Last Updated: Dec 19, 2025

A Freeze-Thawing Method to Prepare Chitosan-Polyvinyl alcohol Hydrogels Without Crosslinking Agents and Diflunisal Release Studies
08:59

A Freeze-Thawing Method to Prepare Chitosan-Polyvinyl alcohol Hydrogels Without Crosslinking Agents and Diflunisal Release Studies

Published on: January 14, 2020

18.7K
Preparation of Expanded Chitin Foams and their Use in the Removal of Aqueous Copper
06:36

Preparation of Expanded Chitin Foams and their Use in the Removal of Aqueous Copper

Published on: February 27, 2021

4.0K
Fabrication of Size-Controlled and Emulsion-Free Chitosan-Genipin Microgels for Tissue Engineering Applications
05:26

Fabrication of Size-Controlled and Emulsion-Free Chitosan-Genipin Microgels for Tissue Engineering Applications

Published on: April 13, 2022

3.8K

Area of Science:

  • Materials Science
  • Chemical Engineering
  • Agricultural Science

Background:

  • Urea release from soil conditioners is crucial for efficient fertilization.
  • Existing models may not fully capture complex release dynamics.
  • Chitosan-based hydrogels offer potential for controlled fertilizer delivery.

Purpose of the Study:

  • To calibrate a theoretical multifractal model for urea release from soil conditioners.
  • To validate the multifractal model using empirical data.
  • To establish the mechanism of urea release from chitosan-salicylaldehyde hydrogels.

Main Methods:

  • Preparation of chitosan-salicylaldehyde hydrogels with varying urea concentrations.
  • Morphological characterization using scanning electron microscopy and polarized light microscopy.
  • In vitro urea release studies in a simulated environment and fitting data to five mathematical models (Korsmeyer-Peppas, Zero order, First order, Higuchi, Hixson-Crowell).

Main Results:

  • The multifractal model was successfully calibrated using empirical urea release data.
  • The calibrated multifractal model showed good agreement with experimental results.
  • Analysis of release kinetics identified the urea release mechanism.

Conclusions:

  • The multifractal model provides a robust framework for understanding and predicting urea release from soil conditioners.
  • This study validates the application of multifractal analysis in fertilizer release studies.
  • The findings contribute to the development of advanced soil conditioning systems for optimized nutrient management.