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Related Concept Videos

Computed Tomography01:10

Computed Tomography

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Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
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Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

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DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
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Related Experiment Video

Updated: Dec 19, 2025

Determining the Functional Status of the Corticospinal Tract Within One Week of Stroke
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Determining Corticospinal Tract Injury from Stroke Using Computed Tomography.

Timothy K Lam1,2, Daniel K Cheung1,2, Seth A Climans3,4

  • 1Heart and Stroke Foundation Canadian Partnership for Stroke Recovery, Toronto, ON, Canada.

The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques
|June 5, 2020
PubMed
Summary

Computed tomography (CT) scans can assess corticospinal tract (CST) injury after stroke, correlating with motor deficits. This study demonstrates CT-based CST injury predicts motor impairment variability in stroke survivors.

Keywords:
Computed tomographyCorticospinal tractMagnetic resonance imagingMotorStroke

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Area of Science:

  • Neuroscience
  • Radiology
  • Rehabilitation Medicine

Background:

  • Stroke-induced damage to the corticospinal tract (CST) causes motor deficits.
  • CST Injury, quantified by lesion overlap, correlates with motor impairment severity.
  • Current research often uses MRI for CST Injury assessment, while CT is standard in acute care.

Purpose of the Study:

  • To determine if CST Injury, assessed using CT scans, explains motor impairment variability post-stroke.
  • To explore the utility of routine clinical CT scans in quantifying stroke-related motor deficits.

Main Methods:

  • Thirty-seven stroke participants with acute CT scans and motor assessments were included.
  • CT images were registered to MRI space for lesion analysis.
  • Stepwise regression analyzed CST Injury and demographics for motor impairment prediction.

Main Results:

  • CST Injury derived from CT scans showed modest evidence of explaining motor impairment variability (R2adj = 0.12, p = 0.02).
  • Demographic variables did not significantly contribute to the model.

Conclusions:

  • This study establishes a link between CST Injury, assessed via CT scans, and motor impairment post-stroke.
  • CT-derived CST Injury shows potential as a biomarker for stroke motor recovery, warranting further investigation.