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Acute ischemic stroke and COVID-19

Catherine Hassett1, Aron Gedansky1, MaryAnn Mays2

  • 1Resident, Cleveland Clinic.

Cleveland Clinic Journal of Medicine
|June 5, 2020
PubMed

Insights

Ischemic stroke can be an initial symptom of COVID-19, particularly in severe cases which may raise the risk of large-artery strokes. Further research is required to confirm these findings and guide effective patient management strategies.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Cardiovascular Medicine

Background:

  • The emergence of Coronavirus Disease 2019 (COVID-19) has been linked to various neurological complications.
  • Ischemic stroke has been anecdotally reported as a presenting manifestation of COVID-19.

Purpose of the Study:

  • To explore the association between COVID-19 and ischemic stroke.
  • To investigate the potential link between severe COVID-19 and large-artery strokes.
  • To highlight the need for further research into the etiology and management of COVID-19-associated strokes.

Main Methods:

  • Review of current literature and case reports.
  • Analysis of epidemiological data on stroke incidence in COVID-19 patients.
  • Comparative analysis of stroke subtypes in relation to COVID-19 severity.

Main Results:

  • Ischemic stroke can be an early clinical sign of COVID-19 infection.
  • Severe COVID-19 disease appears to correlate with an increased risk of large-artery ischemic strokes.
  • The precise mechanisms underlying this association require further elucidation.

Conclusions:

  • COVID-19 may present with ischemic stroke, necessitating heightened clinical awareness.
  • Severe cases of COVID-19 may predispose individuals to specific types of stroke.
  • Additional evidence is crucial for understanding the pathophysiology and optimizing treatment strategies for stroke in the context of COVID-19.

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