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Updated: Dec 19, 2025

A Protocol for Rapid Post-mortem Cell Culture of Diffuse Intrinsic Pontine Glioma DIPG

A Protocol for Rapid Post-mortem Cell Culture of Diffuse Intrinsic Pontine Glioma DIPG

Published on: March 7, 2017

Primary pediatric cerebellar gliosarcoma.

Syed Sarmad Bukhari¹, Muhammad Junaid², Ali Afzal²

¹Department of Neurosurgery, Aga Khan University Hospital, Karachi, Pakistan.

Surgical Neurology International

|June 5, 2020

Summary

This summary is machine-generated.

This case study details a rare infratentorial primary gliosarcoma in a 12-year-old boy. The aggressive tumor required surgical resection and shunt placement, recurring two years later.

Keywords:

Gliosarcoma Pediatric Primary

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Area of Science:

Neuro-oncology
Pediatric Neurosurgery

Background:

Primary gliosarcomas are rare central nervous system tumors.
Infratentorial gliosarcomas are exceptionally uncommon, particularly in pediatric patients.

Observation:

A 12-year-old male presented with symptoms including headache, ataxia, and vomiting.
Magnetic resonance imaging revealed a posterior fossa lesion.

Findings:

The patient underwent ventriculoperitoneal shunt placement and suboccipital craniectomy for a primary gliosarcoma.
The tumor recurred two years post-initial resection, necessitating further intervention.

Implications:

This case highlights the aggressive nature and potential for recurrence of pediatric infratentorial gliosarcomas.
Management may involve complex surgical procedures and repeated interventions.