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Updated: Dec 19, 2025
A Protocol for Rapid Post-mortem Cell Culture of Diffuse Intrinsic Pontine Glioma DIPG
Published on: March 7, 2017
Primary pediatric cerebellar gliosarcoma
Syed Sarmad Bukhari1, Muhammad Junaid2, Ali Afzal2
1Department of Neurosurgery, Aga Khan University Hospital, Karachi, Pakistan.
Insights
This case study details a rare infratentorial primary gliosarcoma in a 12-year-old boy. The aggressive tumor required surgical resection and shunt placement, recurring two years later.
Area of Science:
- Neuro-oncology
- Pediatric Neurosurgery
Background:
- Primary gliosarcomas are rare central nervous system tumors.
- Infratentorial gliosarcomas are exceptionally uncommon, particularly in pediatric patients.
Observation:
- A 12-year-old male presented with symptoms including headache, ataxia, and vomiting.
- Magnetic resonance imaging revealed a posterior fossa lesion.
Findings:
- The patient underwent ventriculoperitoneal shunt placement and suboccipital craniectomy for a primary gliosarcoma.
- The tumor recurred two years post-initial resection, necessitating further intervention.
Implications:
- This case highlights the aggressive nature and potential for recurrence of pediatric infratentorial gliosarcomas.
- Management may involve complex surgical procedures and repeated interventions.
Background:
Primary gliosarcomas of the central nervous are rare and very few have been reported in the infratentorial compartment. Here, we describe such a lesion in a 12-year-old male.
Case Description:
A 12-year-old male presented with headache, ataxia, and vomiting. When Magnetic resonance studies documented a posterior fossa lesion, he underwent placement of a right ventriculoperitoneal shunt followed by a suboccipital craniectomy. The lesion proved to be a primary gliosarcoma. Unfortunately, it recurred 2 years later and required repeated resection.
Conclusion:
Here, we reviewed the rare case of a 12-year-old male requiring shunt placement and suboccipital craniectomy for a primary gliosarcoma that recurred 2 years later.
