[Limits of kinematic alignment and recommendations for its safe application]

Despite the growing clinical evidence "pro" kinematic alignment (KA) in primary total knee arthroplasty, the idea of this individualized implant positioning has not (yet) become established throughout the community. Many surgeons have concerns about the safety of the method and the universality of its application. Interestingly, comparative studies with unlimited indications for KA showed only little or no advantage over standard mechanical alignment in contrast to studies with strict indications showing a significant benefit.

This results in a discussion about possible indication limits for KA. The aim of this article is to summarize the current evidence and theoretical considerations regarding ideal and possibly non-ideal patients. Furthermore, the paper describes the "lessons learned" of the past years as a recommendation for safe use of the method.

Based on current evidence, primary varus osteoarthritis appears to be a good indication for KA. A limitation, however, is extra-articular deformities that lead to a pathologically joint line angle. Instabilities of the collateral ligaments are to be considered as a contraindication. In contrast to varus type osteoarthritis, valgus deformities appear to be more critical for KA. Even though there is yet only limited evidence, especially the accompanying extra-articular pathologies of the hip and ankle pose an increased risk of failure. In our opinion, a restricted KA with an individualized component position but neutral overall limb alignment makes sense here. To analyze the suitability of KA and estimate the post-operative component position, weight-bearing long-leg x‑rays are recommended. Additional stress radiography is helpful in certain cases, as is the three-dimensional analysis of the anatomy by CT or MRI scans.