Related Experiment Video
Updated: Dec 19, 2025
Author Spotlight: Exploring ShiDuGao's Multi-Target Approach in Anus Eczema Treatment
Published on: January 12, 2024
[Analysis of 131 cases of COVID-19 treated with Ganlu Xiaodu Decoction]
Ling Chen1, Zhi-Qiang Cheng2, Fang Liu3
1Department of Pharmacy, Wuhan Third Hospital (Tongren Hospital of Wuhan University) Wuhan 430060, China.
Insights
Ganlu Xiaodu Decoction combined with other Chinese and Western medicines effectively treated COVID-19 patients. All 131 inpatients in Wuhan Third Hospital achieved full recovery and were discharged, indicating promising treatment outcomes.
Area of Science:
- Integrative Medicine
- Infectious Disease Research
- Clinical Pharmacology
Background:
- Coronavirus disease 2019 (COVID-19) presented a significant global health challenge.
- Effective treatment strategies for COVID-19 are crucial for patient recovery and public health.
- Traditional Chinese Medicine (TCM) combined with Western medicine offers a potential avenue for COVID-19 treatment.
Purpose of the Study:
- To evaluate the efficacy of Ganlu Xiaodu Decoction combined with conventional therapies in treating COVID-19 inpatients.
- To analyze the demographic and clinical characteristics of patients treated with this combined regimen.
- To identify common drug combinations and assess their effectiveness.
Main Methods:
- Retrospective analysis of 131 COVID-19 inpatient records from Wuhan Third Hospital.
- Data collected from Donghua Hospital information management and Meikang clinical pharmacy systems.
- Statistical analysis using Excel 2003 and SPSS Clementine 12.0, with Apriori algorithm for association rule mining.
Main Results:
- All 131 COVID-19 patients treated with Ganlu Xiaodu Decoction and other Western/Chinese medicines were cured and discharged.
- Commonly used drugs included Ganlu Xiaodu Decoction, abidor, Lianhua Qingwen, moxifloxacin, and vitamin C.
- Association rule analysis suggested a regular pattern in the drug combinations used.
Conclusions:
- The combination of Ganlu Xiaodu Decoction with other Chinese and Western medicines demonstrated effectiveness in treating COVID-19.
- The observed treatment regimen showed a high cure rate, with all patients recovering and being discharged.
- Further research is warranted to rigorously verify the rationality and safety of these drug combinations.
Abstract:
In this study, Donghua Hospital information management system and Meikang clinical pharmacy management system were used to collect medical records of all inpatients diagnosed as coronavirus disease 2019(COVID-19) in Wuhan Third Hospital. The statistics was based on the data of the cases treated with Ganlu Xiaodu Decoction, including demographic statistics, clinical cha-racteristics before medication, outcome of after medication and efficacy of drug combination. Excel 2003 and SPSS Clementine 12.0 software were used to conduct statistics on the included cases, and Apriori algorithm and association rules were used for the association analysis on drug combination. A total of 131 cases of COVID-19 were treated with Ganlu Xiaodu Decoction combined with Chinese and Western medicine. All of the patients were cured and discharged. The drug combination mainly included Ganlu Xiaodu Decoction, abidor, Lianhua Qingwen, moxifloxacin, Qiangli Pipa Lu, vitamin C, glycyrrhizinate diammonium, pantoprazole and Shufeng Jiedu. There is a certain regularity and effectiveness in the treatment of COVID-19 infection patients with the combination of Ganlu Xiaodu Decoction and other drugs, but the rationality and safety still need to be further verified.
